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Resting\u2010state functional connectivity analysis of blood oxygen level\u2010dependent functional magnetic resonance imaging is a useful measure of intrinsic neural functioning. We utilized resting\u2010state functional connectivity modeling to analyze the intrinsic connectivity in patients with Parkinson's disease within a vocalization network defined by a previous meta\u2010analysis of speech (Brown et al., 2009). Functional connectivity of this network was assessed in 56 patients with Parkinson's disease and 56 gender\u2010, age\u2010, and movement\u2010matched healthy controls. We also had item 5 and 18 of the UPDRS, and the PDQ\u201039 Communication subscale available for correlation with the voice network connectivity strength in patients. The within\u2010group analyses of connectivity patterns demonstrated a lack of subcortical\u2013cortical connectivity in patients with Parkinson's disease. At the cortical level, we found robust (homotopic) interhemispheric connectivity but only inconsistent evidence for many intrahemispheric connections. When directly contrasted to the control group, we found a significant reduction of connections between the left thalamus and putamen, and cortical motor areas, as well as reduced right superior temporal gyrus connectivity. Furthermore, most symptom measures correlated with right putamen, left cerebellum, left superior temporal gyrus, right premotor, and left Rolandic operculum connectivity in the voice network. The results reflect the importance of (right) subcortical nodes and the superior temporal gyrus in Parkinson's disease, enhancing our understanding of the neurobiological underpinnings of vocalization impairment in Parkinson's disease. <jats:italic>Hum Brain Mapp 36:1951\u20131962, 2015<\/jats:italic>. \u00a9 <jats:bold>2015 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.<\/jats:bold><\/jats:p>","DOI":"10.1002\/hbm.22748","type":"journal-article","created":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T04:59:58Z","timestamp":1422421198000},"page":"1951-1962","source":"Crossref","is-referenced-by-count":51,"title":["The intrinsic resting state voice network in Parkinson's disease"],"prefix":"10.1002","volume":"36","author":[{"given":"Anneliese B.","family":"New","sequence":"first","affiliation":[{"name":"University of Texas Health Science Center at San Antonio, Research Imaging Institute San Antonio Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald A.","family":"Robin","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at San Antonio, Research Imaging Institute San Antonio Texas"},{"name":"University of Texas Health Science Center at San Antonio, Department of Neurology San Antonio Texas"},{"name":"University of Texas Health Science Center at San Antonio, Department of Radiology San Antonio Texas"},{"name":"University of Texas Health Science Center at San Antonio and University of Texas at San Antonio, Joint Program in Biomedical Engineering San Antonio Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy L.","family":"Parkinson","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at San Antonio, Research Imaging Institute San Antonio Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia R.","family":"Eickhoff","sequence":"additional","affiliation":[{"name":"Research Center Julich Institute of Neuroscience and Medicine (INM\u20101) Department of Psychiatry Psychotherapy and Psychosomatics, University Hospital Julich Germany"},{"name":"University Hospital Aachen, Department of Psychiatry, Psychotherapy and Psychosomatics Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Reetz","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Aachen Aachen Germany"},{"name":"Research Center Julich Institute of Neuroscience and Medicine (INM\u20104) Department of Neurology University Hospital Julich Germany"},{"name":"Julich Aachen Research Alliance Translational Brain Medicine Julich and Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Hoffstaedter","sequence":"additional","affiliation":[{"name":"Research Center Julich Institute of Neuroscience and Medicine (INM\u20101) Department of Psychiatry Psychotherapy and Psychosomatics, University Hospital Julich Germany"},{"name":"Department of Clinical Neuroscience and Medical Psychology Heinrich Heine University\u2013D\u00fcsseldorf Dusseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mathys","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University Dusseldorf, Medical Faculty Dusseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Sudmeyer","sequence":"additional","affiliation":[{"name":"Department of Neurology Heinrich Heine University \u2013 Dusseldorf, University Hospital Dusseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Michely","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cologne University Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Caspers","sequence":"additional","affiliation":[{"name":"Research Center Julich Institute of Neuroscience and Medicine (INM\u20101) Department of Psychiatry Psychotherapy and Psychosomatics, University Hospital Julich Germany"},{"name":"Department of Diagnostic and Interventional Radiology University Dusseldorf, Medical Faculty Dusseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Grefkes","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cologne University Cologne Germany"},{"name":"Max\u2010Planck\u2010Institute for Neurological Research Neuromodulation, and Neurorehabilitation Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles R.","family":"Larson","sequence":"additional","affiliation":[{"name":"Northwestern University, Communication Sciences and Disorders Evanston Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loraine O.","family":"Ramig","sequence":"additional","affiliation":[{"name":"Department of Speech Language and Hearing Science, University of Colorado \u2013 Boulder Colorado"},{"name":"National Center for Voice and Speech Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter T.","family":"Fox","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at San Antonio, Research Imaging Institute San Antonio Texas"},{"name":"University of Texas Health Science Center at San Antonio, Department of Neurology San Antonio Texas"},{"name":"University of Texas Health Science Center at San Antonio, Department of Radiology San Antonio Texas"},{"name":"South Texas Veterans Health Care System, Department of Neurology San Antonio Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon 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