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Given advances in the imaging sciences, a new era of discovery is underway, with potential to transform the understanding of healthy processing as well as the ability to treat disorders. Coactivation\u2010based parcellation, a meta\u2010analytic approach, and ultra\u2010high field, high\u2010resolution functional and structural neuroimaging to characterize the neurofunctional topography of the hippocampus was employed. Data revealed strong support for an evolutionarily preserved topography along the long\u2010axis. Specifically, the left hippocampus was segmented into three distinct clusters: an emotional processing cluster supported by structural and functional connectivity to the amygdala and parahippocampal gyrus, a cognitive operations cluster, with functional connectivity to the anterior cingulate and inferior frontal gyrus, and a posterior perceptual cluster with distinct structural connectivity patterns to the occipital lobe coupled with functional connectivity to the precuneus and angular gyrus. The right hippocampal segmentation was more ambiguous, with plausible 2\u2010 and 5\u2010cluster solutions. Segmentations shared connectivity with brain regions known to support the correlated processes. This represented the first neurofunctional topographic model of the hippocampus using a robust, bias\u2010free, multimodal approach. <jats:italic>Hum Brain Mapp 36:5018\u20135037, 2015<\/jats:italic>. \u00a9 <jats:bold>2015 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p>","DOI":"10.1002\/hbm.22987","type":"journal-article","created":{"date-parts":[[2015,9,9]],"date-time":"2015-09-09T09:14:27Z","timestamp":1441790067000},"page":"5018-5037","source":"Crossref","is-referenced-by-count":119,"title":["Neurofunctional topography of the human hippocampus"],"prefix":"10.1002","volume":"36","author":[{"given":"Jennifer L.","family":"Robinson","sequence":"first","affiliation":[{"name":"Department of Psychology Auburn University 226 Thach Hall Auburn Alabama"},{"name":"Department of Electrical and Computer Engineering Auburn University, Auburn University Magnetic Resonance Imaging Research Center 560 Devall Drive Auburn Alabama"},{"name":"Department of Kinesiology Auburn University 226 Thach Hall Auburn Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel S.","family":"Barron","sequence":"additional","affiliation":[{"name":"Yale University School of Medicine New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A. 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