{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T11:26:30Z","timestamp":1794655590130,"version":"4.9.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,10,5]],"date-time":"2015-10-05T00:00:00Z","timestamp":1444003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"University of Pittsburgh Brain Institute"},{"name":"NIH","award":["R01DC013803-01A1"],"award-info":[{"award-number":["R01DC013803-01A1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The superior fronto\u2010occipital fasciculus (SFOF), a long association bundle that connects frontal and occipital lobes, is well\u2010documented in monkeys but is controversial in human brain. Its assumed role is in visual processing and spatial awareness. To date, anatomical and neuroimaging studies on human and animal brains are not in agreement about the existence, course, and terminations of SFOF. To clarify the existence of the SFOF in human brains, we applied deterministic fiber tractography to a template of 488 healthy subjects and to 80 individual subjects from the Human Connectome Project (HCP) and validated the results with white matter microdissection of post\u2010mortem human brains. The imaging results showed that previous reconstructions of the SFOF were generated by two false continuations, namely between superior thalamic peduncle (STP) and stria terminalis (ST), and ST and posterior thalamic peduncle. The anatomical microdissection confirmed this finding. No other fiber tracts in the previously described location of the SFOF were identified. Hence, our data suggest that the SFOF does not exist in the human brain.\n                    <jats:italic>Hum Brain Mapp 36:4964\u20134971, 2015<\/jats:italic>\n                    . \u00a9\n                    <jats:bold>2015 Wiley Periodicals, Inc.<\/jats:bold>\n                  <\/jats:p>","DOI":"10.1002\/hbm.22990","type":"journal-article","created":{"date-parts":[[2015,10,5]],"date-time":"2015-10-05T06:18:48Z","timestamp":1444025928000},"page":"4964-4971","source":"Crossref","is-referenced-by-count":61,"title":["The controversial existence of the human superior fronto\u2010occipital fasciculus: Connectome\u2010based tractographic study with microdissection validation"],"prefix":"10.1002","volume":"36","author":[{"given":"Antonio","family":"Meola","sequence":"first","affiliation":[{"name":"Department of Neurosurgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania"},{"name":"Department of Neurosurgery University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayhan","family":"Comert","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania"},{"name":"Department of Anatomy Ankara University School of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang\u2010Cheng","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Psychology Carnegie Mellon University Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Stefaneanu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C.","family":"Fernandez\u2010Miranda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1105"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2013.10.009"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199541164.001.0001"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.10130"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200312020-00021"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh423"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000333767.05328.49"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182592faa"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2012.09.005"},{"key":"e_1_2_8_11_1","first-page":"356","article-title":"Diffusion tensor imaging of cerebral white matter: A pictorial review of physics, fiber tract anatomy, and tumor imaging patterns","volume":"25","author":"Jellison BJ","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn250"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20683"},{"key":"e_1_2_8_14_1","first-page":"36","volume-title":"Atlas cerebri humani. Der innere Bau des Gehirns dargestellt auf Grund makroskopischer Pr\u00e4parate. The Inner Structure of the Brain Demonstrated on the Basis of Macroscopical Preparations","author":"Ludwig E","year":"1956"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.05.042"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10074"},{"key":"e_1_2_8_17_1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/978-3-662-10343-2","volume-title":"The Human Central Nervous System: A Synopsis and Atlas","author":"Nieuwenhuys R","year":"1988"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195104233.001.0001"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/09647040600620468"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl359"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.05.057"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2905"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1405672111"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199706000-00022"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.05.041"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2301021640"},{"key":"e_1_2_8_27_1","first-page":"1665","article-title":"Subcomponents and connectivity of the superior longitudinal fasciculus in the human brain","volume":"220","author":"Wang X","year":"2015","journal-title":"Brain Struct Funct"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1961.00450160014002"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2010.2045126"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080713"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22420"}],"container-title":["Human Brain Mapping"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhbm.22990","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhbm.22990","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.22990","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hbm.22990","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.22990","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T16:00:21Z","timestamp":1694102421000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hbm.22990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,5]]},"references-count":30,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1002\/hbm.22990"],"URL":"https:\/\/doi.org\/10.1002\/hbm.22990","archive":["Portico"],"relation":{},"ISSN":["1065-9471","1097-0193"],"issn-type":[{"value":"1065-9471","type":"print"},{"value":"1097-0193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,5]]}}}