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Symptoms include fatigue, as well as problems associated with vision and movement. Although areas of demyelination in white matter are observed routinely in patients undergoing MRI scans, such measures are often a poor predictor of disease severity. For this reason, it is instructive to measure associated changes in brain function. Widespread white\u2010matter demyelination may lead to delays of propagation of neuronal activity, and with its excellent temporal resolution, magnetoencephalography can be used to probe such delays in controlled conditions (e.g., during a task). In healthy subjects, responses to visuomotor tasks are well documented: in motor cortex, movement elicits a localised decrease in the power of beta band oscillations (event\u2010related beta desynchronisation) followed by an increase above baseline on movement cessation (post\u2010movement beta rebound (PMBR)). In visual cortex, visual stimulation generates increased gamma oscillations. In this study, we use a visuomotor paradigm to measure these responses in MS patients and compare them to age\u2010 and gender\u2010matched healthy controls. We show a significant increase in the time\u2010to\u2010peak of the PMBR in patients which correlates significantly with the symbol digit modalities test: a measure of information processing speed. A significant decrease in the amplitude of visual gamma oscillations in patients is also seen. These findings highlight the potential value of electrophysiological imaging in generating a new understanding of visual disturbances and abnormal motor control in MS patients.\n                    <jats:italic>Hum Brain Mapp 38:2441\u20132453, 2017<\/jats:italic>\n                    . \u00a9\n                    <jats:bold>2017 Wiley Periodicals, Inc.<\/jats:bold>\n                  <\/jats:p>","DOI":"10.1002\/hbm.23531","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T07:49:55Z","timestamp":1488181795000},"page":"2441-2453","source":"Crossref","is-referenced-by-count":43,"title":["Abnormal task driven neural oscillations in multiple sclerosis: A visuomotor MEG study"],"prefix":"10.1002","volume":"38","author":[{"given":"Eleanor L.","family":"Barratt","sequence":"first","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prejaas K.","family":"Tewarie","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margareta A.","family":"Clarke","sequence":"additional","affiliation":[{"name":"Division of Clinical Neurology Queen's Medical Centre, University of Nottingham Nottingham NG7 2UH United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma L.","family":"Hall","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penny A.","family":"Gowland","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter G.","family":"Morris","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan T.","family":"Francis","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikos","family":"Evangelou","sequence":"additional","affiliation":[{"name":"Division of Clinical Neurology Queen's Medical Centre, University of Nottingham Nottingham NG7 2UH United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8687-8185","authenticated-orcid":false,"given":"Matthew J.","family":"Brookes","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham Nottingham NG7 2RD United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2004.03495.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2007.10.017"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200206000-00003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.8.2.145"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.01.050"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.10.074"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1112685108"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-062111-150444"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2010.93"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1007-16.2016"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200112040-00051"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv209"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.04.178"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.08.048"},{"key":"e_1_2_7_16_1","unstructured":"Delis D. 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