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While progress has been made in elucidating the function of these connections, our understanding of their structure in humans remains sparse and non\u2010systematic. Harnessing diffusion\u2010weighted imaging and probabilistic tractography in humans, we investigate connections between two main amygdala nucleus groups, thalamic nuclei, and cortex. We first parcellated amygdala into deep (basolateral) and superficial (centrocortical) nucleus groups, and thalamus into six subregions, using previously established protocols based on connectivity. Cortex was parcellated based on T1\u2010weighted images. We found substantial amygdala connections to thalamus, with different patterns for the two amygdala nuclei. Crucially, we describe direct subcortical connections between amygdala and paraventricular thalamus. Different from rodents but similar to non\u2010human primates, these are more pronounced for basolateral than centrocortical amygdala. Substantial white\u2010matter connectivity between amygdala and visual pulvinar is also more pronounced for basolateral amygdala. Furthermore, we establish detailed connectivity profiles for basolateral and centrocortical amygdala to cortical regions. These exhibit cascadic connections with sensory cortices as suggested previously based on tracer methods in non\u2010human animals. We propose that the quantitative connectivity profiles provided here may guide future work on normal and pathological function of human amygdala.<jats:italic>Hum Brain Mapp 38:3927\u20133940, 2017<\/jats:italic>. \u00a9<jats:bold>2017 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p>","DOI":"10.1002\/hbm.23639","type":"journal-article","created":{"date-parts":[[2017,5,17]],"date-time":"2017-05-17T07:27:34Z","timestamp":1495006054000},"page":"3927-3940","source":"Crossref","is-referenced-by-count":77,"title":["Deconstructing white matter connectivity of human amygdala nuclei with thalamus and cortex subdivisions in vivo"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3946-7057","authenticated-orcid":false,"given":"Aslan","family":"Abivardi","sequence":"first","affiliation":[{"name":"Department of Psychiatry Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich Zurich 8032 Switzerland"},{"name":"Division of Clinical Psychiatry 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