{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T20:40:03Z","timestamp":1779223203186,"version":"3.51.4"},"reference-count":47,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,5,15]],"date-time":"2017-05-15T00:00:00Z","timestamp":1494806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31671169\/31530031"],"award-info":[{"award-number":["31671169\/31530031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"publisher","award":["201564\/000099"],"award-info":[{"award-number":["201564\/000099"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["U54 NS067501"],"award-info":[{"award-number":["U54 NS067501"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Cervical dystonia (CD) is a neurological disorder with typical symptoms of involuntary and abnormal movements and postures of the head. CD\u2010associated alterations of functional brain networks have not been well characterized. Previous studies of CD using resting\u2010state functional MRI (rfMRI) are limited in two aspects: (i) the analyses were not directly focused on the functional brain network related to head movement and (ii) rfMRI measurements other than functional connectivity (FC) were not investigated. The present study examined alterations of FC in CD by capitalizing on newly identified brain regions supporting isometric head rotation (Prudente et al.: J Neurosci 35 (2015) 9163\u20139172). In addition to FC, which only reflects inter\u2010regional signal synchronization, local, or intraregional alterations were also examined using rfMRI measurements of the fractional amplitude of low\u2010frequency fluctuations and regional homogeneity (ReHo). Finally, with alterations of different rfMRI measures identified, a support vector machine (SVM) learning algorithm was implemented for group classification. The results revealed both inter\u2010 (FC) and intra\u2010regional (ReHo) alterations extensively distributed in both cortical and subcortical structures; and common alterations of these measures were identified bilaterally in the postcentral gyrus as well as in the basal ganglia and thalamus. Of the rfMRI features examined, seven of them (four FC and three ReHo measures) survived the SVM procedure of recursive feature elimination and together provided the highest group classification accuracy of 90.6%. The present findings extend previous studies of rfMRI in CD and offer insight into the underlying pathophysiology of the disorder in relation to network dysfunction and somatosensory disturbances.\n                    <jats:italic>Hum Brain Mapp 38:4098\u20134108, 2017<\/jats:italic>\n                    . \u00a9\n                    <jats:bold>2017 Wiley Periodicals, Inc.<\/jats:bold>\n                  <\/jats:p>","DOI":"10.1002\/hbm.23651","type":"journal-article","created":{"date-parts":[[2017,5,15]],"date-time":"2017-05-15T07:28:38Z","timestamp":1494833318000},"page":"4098-4108","source":"Crossref","is-referenced-by-count":51,"title":["Alterations of resting\u2010state fMRI measurements in individuals with cervical dystonia"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6009-7903","authenticated-orcid":false,"given":"Zhihao","family":"Li","sequence":"first","affiliation":[{"name":"School of Psychology and Sociology, Shenzhen University Shenzhen Guangdong People's Republic of China"},{"name":"Shenzhen Key Laboratory of Affective and Social Cognitive Science Shenzhen University Shenzhen Guangdong People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cec\u00edlia N.","family":"Prudente","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine University of Minnesota Minneapolis Minnesota"},{"name":"Department of Neurology Emory University Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall","family":"Stilla","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Sathian","sequence":"additional","affiliation":[{"name":"Department of Neurology Emory University Atlanta Georgia"},{"name":"Department of Rehabilitation Medicine Emory University Atlanta Georgia"},{"name":"Department Psychology Emory University Atlanta Georgia"},{"name":"Rehabilitation R&amp;D Center for Visual &amp; Neurocognitive Rehabilitation, Atlanta VAMC Decatur Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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