{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:44:08Z","timestamp":1786977848974,"version":"build-2736575974"},"reference-count":77,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T00:00:00Z","timestamp":1495497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We studied the neural mechanisms that are engaged during the experience of beauty derived from sorrow and from joy, two experiences that share a common denominator (beauty) but are linked to opposite emotional valences. Twenty subjects viewed and rerated, in a functional magnetic resonance imaging scanner, 120 images which each had classified into the following four categories: beautiful and sad; beautiful and joyful; neutral; ugly. The medial orbito\u2010frontal cortex (mOFC) was active during the experience of both types of beauty. Otherwise, the two experiences engaged different parts of the brain: joyful beauty engaged areas linked to positive emotions while sorrowful beauty engaged areas linked to negative experiences. Separate regions of the cerebellum were engaged during experience of the two conditions. A functional connectivity analysis indicated that the activity within the mOFC was modulated by the supplementary motor area\/middle cingulate cortex, known to be engaged during empathetic experiences provoked by other peoples' sadness.\n                    <jats:italic>Hum Brain Mapp 38:4185\u20134200, 2017<\/jats:italic>\n                    . \u00a9\n                    <jats:bold>2017 Wiley Periodicals, Inc.<\/jats:bold>\n                  <\/jats:p>","DOI":"10.1002\/hbm.23657","type":"journal-article","created":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T20:54:35Z","timestamp":1495572875000},"page":"4185-4200","source":"Crossref","is-referenced-by-count":56,"title":["The experience of beauty derived from sorrow"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7107-657X","authenticated-orcid":false,"given":"Tomohiro","family":"Ishizu","sequence":"first","affiliation":[{"name":"Wellcome Laboratory of Neurobiology, Department of Cell and Developmental Biology University College London London United Kingdom"},{"name":"Japan Society for the Promotion of Science Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semir","family":"Zeki","sequence":"additional","affiliation":[{"name":"Wellcome Laboratory of Neurobiology, Department of Cell and Developmental Biology University College London London United 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