{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:09:00Z","timestamp":1790615340157,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T00:00:00Z","timestamp":1498608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Our purpose was to validate a reliable method to capture brain activity concomitant with hallucinatory events, which constitute frequent and disabling experiences in schizophrenia. Capturing hallucinations using functional magnetic resonance imaging (fMRI) remains very challenging. We previously developed a method based on a two\u2010steps strategy including (1) multivariate data\u2010driven analysis of per\u2010hallucinatory fMRI recording and (2) selection of the components of interest based on a post\u2010fMRI interview. However, two tests still need to be conducted to rule out critical pitfalls of conventional fMRI capture methods before this two\u2010steps strategy can be adopted in hallucination research: replication of these findings on an independent sample and assessment of the reliability of the hallucination\u2010related patterns at the subject level. To do so, we recruited a sample of 45 schizophrenia patients suffering from frequent hallucinations, 20 schizophrenia patients without hallucinations and 20 matched healthy volunteers; all participants underwent four different experiments. The main findings are (1) high accuracy in reporting unexpected sensory stimuli in an MRI setting; (2) good detection concordance between hypothesis\u2010driven and data\u2010driven analysis methods (as used in the two\u2010steps strategy) when controlled unexpected sensory stimuli are presented; (3) good agreement of the two\u2010steps method with the online button\u2010press approach to capture hallucinatory events; (4) high spatial consistency of hallucinatory\u2010related networks detected using the two\u2010steps method on two independent samples. By validating the two\u2010steps method, we advance toward the possible transfer of such technology to new image\u2010based therapies for hallucinations. <jats:italic>Hum Brain Mapp 38:4966\u20134979, 2017<\/jats:italic>. \u00a9 <jats:bold>2017 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p>","DOI":"10.1002\/hbm.23707","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T04:29:14Z","timestamp":1498710554000},"page":"4966-4979","source":"Crossref","is-referenced-by-count":27,"title":["fMRI capture of auditory hallucinations: Validation of the two\u2010steps method"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1941-6474","authenticated-orcid":false,"given":"Arnaud","family":"Leroy","sequence":"first","affiliation":[{"name":"Univ Lille, CNRS, UMR 9193 \u2010 SCALab \u2010 Sciences Cognitives et Sciences Affectives Lille F\u201059000 France"},{"name":"CHU Lille, Psychiatry Dpt., CURE platform Lille F\u201059000 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