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However, resting\u2010state network (RSN) disruptions have not been systematically compared between the two disorders. Further, the impact of RSN disruptions on social cognition, a key determinant of functional outcome, has not been studied. Forty\u2010eight individuals with schizophrenia, 46 with bipolar disorder, and 48 healthy controls completed resting\u2010state functional magnetic resonance imaging. An atlas\u2010based approach was used to examine functional connectivity within nine RSNs across the cortex. RSN connectivity was assessed via nonparametric permutation testing, and associations with performance on emotion perception, mentalizing, and emotion management tasks were examined. Group differences were observed in the medial and lateral visual networks and the sensorimotor network. Individuals with schizophrenia demonstrated reduced connectivity relative to healthy controls in all three networks. Individuals with bipolar disorder demonstrated reduced connectivity relative to controls in the medial visual network and connectivity within this network was significantly positively correlated with emotion management. In healthy controls, connectivity within the medial and lateral visual networks positively correlated with mentalizing. No significant correlations were found for either visual network in schizophrenia. Results highlight the role of altered early visual processing in social cognitive deficits in both schizophrenia and bipolar disorder. However, individuals with bipolar disorder appear to compensate for disrupted visual network connectivity on social cognitive tasks, whereas those with schizophrenia do not. The current study adds clarity on the neurophysiology underlying social cognitive deficits that result in impaired functioning in serious mental illness.<\/jats:p>","DOI":"10.1002\/hbm.24731","type":"journal-article","created":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T14:59:28Z","timestamp":1563548368000},"page":"4703-4715","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Linking resting\u2010state networks and social cognition in schizophrenia and bipolar disorder"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6077-1307","authenticated-orcid":false,"given":"Amy M.","family":"Jimenez","sequence":"first","affiliation":[{"name":"Desert Pacific MIRECC VA Greater Los Angeles Healthcare System Los Angeles California"},{"name":"Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Riedel","sequence":"additional","affiliation":[{"name":"Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles Los Angeles California"},{"name":"Department of Psychiatry and Psychotherapy Technische Universit\u00e4t Dresden Dresden Sachsen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9567-8700","authenticated-orcid":false,"given":"Junghee","family":"Lee","sequence":"additional","affiliation":[{"name":"Desert Pacific MIRECC VA Greater Los Angeles Healthcare System Los Angeles California"},{"name":"Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Reavis","sequence":"additional","affiliation":[{"name":"Desert Pacific MIRECC VA Greater Los Angeles Healthcare System Los Angeles California"},{"name":"Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael F.","family":"Green","sequence":"additional","affiliation":[{"name":"Desert Pacific MIRECC VA Greater Los Angeles Healthcare System Los Angeles California"},{"name":"Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-013-0698-0"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3620-15.2016"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2009.08.040"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858411403316"},{"issue":"1","key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: A practical and powerful approach to multiple testing","volume":"57","author":"Benjamini Y.","year":"1995","journal-title":"Journal of the Royal Statistical Society. 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