{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T19:26:15Z","timestamp":1785439575098,"version":"3.56.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:00:00Z","timestamp":1578268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AT009829"],"award-info":[{"award-number":["R01 AT009829"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DA038895"],"award-info":[{"award-number":["R01 DA038895"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC61871420"],"award-info":[{"award-number":["NSFC61871420"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The brain frontoparietal regions and the functional communications between them are critical in supporting working memory and other executive functions. The functional connectivity between frontoparietal regions are modulated by working memory loads, and are shown to be modulated by a third brain region in resting\u2010state. However, it is largely unknown whether the third\u2010region modulations remain the same during working memory tasks or were largely modulated by task demands. In the current study, we collected functional MRI (fMRI) data when the subjects were performing n\u2010back tasks and in resting\u2010state. We first used a block\u2010designed localizer to define the frontoparietal regions that showed higher activations in the 2\u2010back than the 1\u2010back condition. Next, we performed physiophysiological interaction (PPI) analysis using left and right middle frontal gyrus (MFG) and superior parietal lobule (SPL) regions, respectively, in three continuous\u2010designed runs of resting\u2010state, 1\u2010back, and 2\u2010back conditions. No regions showed consistent modulatory interactions with the seed pairs in the three conditions. Instead, the anterior cingulate cortex (ACC) showed different modulatory interactions with the right MFG and SPL among the three conditions. While the increased activity of the ACC was associated with decreased functional coupling between the right MFG and SPL in resting\u2010state, it was associated with increased functional coupling in the 2\u2010back condition. The observed task modulations support the functional significance of the modulations of the ACC on frontoparietal connectivity.<\/jats:p>","DOI":"10.1002\/hbm.24912","type":"journal-article","created":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T14:26:50Z","timestamp":1578320810000},"page":"1797-1805","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Anterior cingulate cortex differently modulates frontoparietal functional connectivity between resting\u2010state and working memory tasks"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2422-9016","authenticated-orcid":false,"given":"Xin","family":"Di","sequence":"first","affiliation":[{"name":"School of Life Sciences and Technology, University of Electronic Science and Technology of China  Chengdu China"},{"name":"Department of Biomedical Engineering New Jersey Institute of Technology  Newark New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heming","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Technology, University of Electronic Science and Technology of China  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3710-3500","authenticated-orcid":false,"given":"Bharat B","family":"Biswal","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Technology, University of Electronic Science and Technology of China  Chengdu China"},{"name":"Department of Biomedical Engineering New Jersey Institute of Technology  Newark New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.118.4.687"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.05.033"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2005.1634"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911855107"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1364-6613(00)01483-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24399"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2017.00237"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071163"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.367"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00893.2014"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-013-0634-3"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhy055"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504136102"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1997.0291"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910350312"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1019641108"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00058-2"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsu080"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.106.208102"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24633"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20131"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.98.2.676"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0196866"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2005.03.018"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.1997.9.5.648"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.06.012"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.04.262"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.04.006"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068910"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00338.2011"}],"container-title":["Human Brain Mapping"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhbm.24912","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.24912","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hbm.24912","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.24912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T03:48:46Z","timestamp":1693885726000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hbm.24912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,6]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1002\/hbm.24912"],"URL":"https:\/\/doi.org\/10.1002\/hbm.24912","archive":["Portico"],"relation":{},"ISSN":["1065-9471","1097-0193"],"issn-type":[{"value":"1065-9471","type":"print"},{"value":"1097-0193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,6]]},"assertion":[{"value":"2019-08-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}