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The literature to date, however, has largely focused on measuring changes in the spatial organization of functional brain networks. In the present study, changes in the temporal dynamics of BOLD signals are examined throughout concussion recovery using scaling (or fractal) analysis. Imaging data were collected for 228 university\u2010level athletes, 61 with concussion and 167 athletic controls. Concussed athletes were scanned at the acute phase of injury (1\u20137\u2009days postinjury), the subacute phase (8\u201314\u2009days postinjury), medical clearance to return to sport (RTS), 1\u2009month post\u2010RTS and 1\u2009year post\u2010RTS. The wavelet leader multifractal approach was used to assess scaling (<jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>1<\/jats:sub><\/jats:styled-content>) and multifractal (<jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>2<\/jats:sub><\/jats:styled-content>) behavior. Significant longitudinal changes were identified for <jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>1<\/jats:sub><\/jats:styled-content>, which was lowest at acute injury, became significantly elevated at RTS, and returned near control levels by 1\u2009year post\u2010RTS. No longitudinal changes were identified for <jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>2<\/jats:sub><\/jats:styled-content>. Secondary analyses showed that clinical measures of acute symptom severity and time to RTP were related to longitudinal changes in <jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>1<\/jats:sub><\/jats:styled-content>. Athletes with both higher symptoms and prolonged recovery had elevated <jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>1<\/jats:sub><\/jats:styled-content> values at RTS, while athletes with higher symptoms but rapid recovery had reduced <jats:styled-content>\n<jats:italic>c<\/jats:italic><jats:sub>1<\/jats:sub><\/jats:styled-content> at acute injury. This study provides the first evidence for long\u2010term recovery of BOLD scale\u2010free brain dynamics after a concussion.<\/jats:p>","DOI":"10.1002\/hbm.24962","type":"journal-article","created":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T13:34:48Z","timestamp":1588167288000},"page":"2567-2582","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Scale\u2010free functional brain dynamics during recovery from sport\u2010related concussion"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8481-2505","authenticated-orcid":false,"given":"Nathan W.","family":"Churchill","sequence":"first","affiliation":[{"name":"Neuroscience Research Program St. Michael's Hospital  Toronto Canada"},{"name":"Keenan Research Centre for Biomedical Science of St. Michael's Hospital  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael 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