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The temporal variability of the functional connectivity (or dynamic FC) derived from resting\u2010state functional MRI has been suggested as a useful metric for studying abnormal behaviors including ASB. This is the first study using low\u2010frequency fluctuations of the dynamic FC to unravel potential system\u2010level neural correlates with ASB. Specifically, we individually associated the dynamic FC patterns with the ASB scores (measured by Antisocial Process Screening Device) of the male offenders (age: 23.29\u2009\u00b1\u20093.36\u2009years) based on machine learning. Results showed that the dynamic FCs were associated with individual ASB scores. Moreover, we found that it was mainly the inter\u2010network dynamic FCs that were negatively associated with the ASB severity. Three major high\u2010order cognitive functional networks and the sensorimotor network were found to be more associated with ASB. We further found that impaired behavior in the ASB subjects was mainly associated with decreased FC dynamics in these networks, which may explain why ASB subjects usually have impaired executive control and emotional processing functions. Our study shows that temporal variation of the FC could be a promising tool for ASB assessment, treatment, and prevention.<\/jats:p>","DOI":"10.1002\/hbm.25225","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T16:38:20Z","timestamp":1602866300000},"page":"329-344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Dynamic neural circuit disruptions associated with antisocial behaviors"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7968-9351","authenticated-orcid":false,"given":"Weixiong","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Radiology and BRIC University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Department of Information Science and Engineering Hunan First Normal University  Changsha Hunan 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