{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:54:18Z","timestamp":1792457658265,"version":"4.5.0"},"reference-count":181,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T00:00:00Z","timestamp":1613865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U54 EB020403"],"award-info":[{"award-number":["U54 EB020403"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["#223273"],"award-info":[{"award-number":["#223273"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006095","name":"Helse S\u00f8r-\u00d8st RHF","doi-asserted-by":"publisher","award":["#2020060"],"award-info":[{"award-number":["#2020060"]}],"id":[{"id":"10.13039\/501100006095","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The Enhancing NeuroImaging Genetics through Meta\u2010Analysis copy number variant (ENIGMA\u2010CNV) and 22q11.2 Deletion Syndrome Working Groups (22q\u2010ENIGMA WGs) were created to gain insight into the involvement of genetic factors in human brain development and related cognitive, psychiatric and behavioral manifestations. To that end, the ENIGMA\u2010CNV WG has collated CNV and magnetic resonance imaging (MRI) data from ~49,000 individuals across 38 global research sites, yielding one of the largest studies to date on the effects of CNVs on brain structures in the general population. The 22q\u2010ENIGMA WG includes 12 international research centers that assessed over 533 individuals with a confirmed 22q11.2 deletion syndrome, 40 with 22q11.2 duplications, and 333 typically developing controls, creating the largest\u2010ever 22q11.2 CNV neuroimaging data set. In this review, we outline the ENIGMA infrastructure and procedures for multi\u2010site analysis of CNVs and MRI data. So far, ENIGMA has identified effects of the 22q11.2, 16p11.2 distal, 15q11.2, and 1q21.1 distal CNVs on subcortical and cortical brain structures. Each CNV is associated with differences in cognitive, neurodevelopmental and neuropsychiatric traits, with characteristic patterns of brain structural abnormalities. Evidence of gene\u2010dosage effects on distinct brain regions also emerged, providing further insight into genotype\u2013phenotype relationships. Taken together, these results offer a more comprehensive picture of molecular mechanisms involved in typical and atypical brain development. This \u201cgenotype\u2010first\u201d approach also contributes to our understanding of the etiopathogenesis of brain disorders. Finally, we outline future directions to better understand effects of CNVs on brain structure and behavior.<\/jats:p>","DOI":"10.1002\/hbm.25354","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T06:40:32Z","timestamp":1613976032000},"page":"300-328","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Effects of copy number variations on brain structure and risk for psychiatric illness: Large\u2010scale studies from the<scp>ENIGMA<\/scp>working groups on<scp>CNVs<\/scp>"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7297-7855","authenticated-orcid":false,"given":"Ida E.","family":"S\u00f8nderby","sequence":"first","affiliation":[{"name":"Department of Medical Genetics Oslo University Hospital Oslo Norway"},{"name":"Norwegian Centre for Mental Disorders Research (NORMENT), Division of Mental Health and Addiction Oslo University Hospital and University of Oslo Oslo Norway"},{"name":"KG Jebsen Centre for Neurodevelopmental Disorders University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2921-3408","authenticated-orcid":false,"given":"Christopher R. K.","family":"Ching","sequence":"additional","affiliation":[{"name":"Imaging Genetics Center Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California Marina del Rey California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0046-4070","authenticated-orcid":false,"given":"Sophia I.","family":"Thomopoulos","sequence":"additional","affiliation":[{"name":"Imaging Genetics Center Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California Marina del Rey California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"van der Meer","sequence":"additional","affiliation":[{"name":"Norwegian Centre for Mental Disorders Research (NORMENT), Division of Mental Health and Addiction Oslo University Hospital and University of Oslo Oslo Norway"},{"name":"School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences Maastricht University Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daqiang","family":"Sun","sequence":"additional","affiliation":[{"name":"Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology University of California Los Angeles Los Angeles California USA"},{"name":"Department of Mental Health Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio E.","family":"Villalon\u2010Reina","sequence":"additional","affiliation":[{"name":"Imaging Genetics Center Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California Marina del Rey California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Agartz","sequence":"additional","affiliation":[{"name":"NORMENT, Institute of Clinical Psychiatry University of Oslo Oslo Norway"},{"name":"Department of Psychiatric Research Diakonhjemmet Hospital Oslo Norway"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Amunts","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Medicine (INM\u20101) Research Centre J\u00fclich J\u00fclich Germany"},{"name":"Cecile and Oskar Vogt Institute for Brain Research, Medical Faculty University Hospital D\u00fcsseldorf, Heinrich\u2010Heine\u2010University D\u00fcsseldorf D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celso","family":"Arango","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Mara\u00f1on, IsSGM, Universidad Complutense, School of Medicine Madrid Spain"},{"name":"Centro Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM) Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola J.","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Mathematics and Statistics Murdoch University Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Ayesa\u2010Arriola","sequence":"additional","affiliation":[{"name":"Centro Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM) Madrid Spain"},{"name":"Department of Psychiatry Marqu\u00e9s de Valdecilla University Hospital, Valdecilla Biomedical Research Institute (IDIVAL) Santander Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geor","family":"Bakker","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neuropsychology Maastricht University Maastricht The Netherlands"},{"name":"Department of Radiology and Nuclear Medicine VU University Medical Center Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne S.","family":"Bassett","sequence":"additional","affiliation":[{"name":"Clinical Genetics Research Program Centre for Addiction and Mental Health Toronto Ontario Canada"},{"name":"Dalglish Family 22q Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Hospital University Health Network Toronto Ontario Canada"},{"name":"Department of Psychiatry University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorret I.","family":"Boomsma","sequence":"additional","affiliation":[{"name":"Department of Biological Psychology Vrije Universiteit Amsterdam Amsterdam The Netherlands"},{"name":"Amsterdam Public Health (APH) Research Institute Amsterdam UMC Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"B\u00fclow","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic Radiology and Neuroradiology University Medicine Greifswald Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy J.","family":"Butcher","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Toronto Toronto Ontario Canada"},{"name":"Child Health Evaluative Sciences The Hospital for Sick Children Research Institute Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vince D.","family":"Calhoun","sequence":"additional","affiliation":[{"name":"Tri\u2010institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS) Georgia State, Georgia Tech, Emory Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svenja","family":"Caspers","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Medicine (INM\u20101) Research Centre J\u00fclich J\u00fclich Germany"},{"name":"Institute for Anatomy I Medical Faculty &amp; University Hospital D\u00fcsseldorf, University of D\u00fcsseldorf D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva W. C.","family":"Chow","sequence":"additional","affiliation":[{"name":"Clinical Genetics Research Program Centre for Addiction and Mental Health Toronto Ontario Canada"},{"name":"Department of Psychiatry University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Cichon","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Medicine (INM\u20101) Research Centre J\u00fclich J\u00fclich Germany"},{"name":"Institute of Medical Genetics and Pathology University Hospital Basel Basel Switzerland"},{"name":"Department of Biomedicine University of Basel Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Ciufolini","sequence":"additional","affiliation":[{"name":"Department of Psychosis Studies Institute of Psychiatry, Psychology and Neuroscience, King's College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Craig","sequence":"additional","affiliation":[{"name":"Department of Forensic and Neurodevelopmental Sciences The Sackler Institute for Translational Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedicto","family":"Crespo\u2010Facorro","sequence":"additional","affiliation":[{"name":"HU Virgen del Rocio, IBIS, Universidad de Sevilla, CIBERSAM Sevilla Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C.","family":"Cunningham","sequence":"additional","affiliation":[{"name":"MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences Cardiff University Cardiff United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders M.","family":"Dale","sequence":"additional","affiliation":[{"name":"Center for Multimodal Imaging and Genetics University of California San Diego La Jolla California USA"},{"name":"Department Radiology University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Dazzan","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Institute of Psychiatry, Psychology and Neuroscience, King's College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greig I.","family":"de Zubicaray","sequence":"additional","affiliation":[{"name":"Faculty of Health Queensland University of Technology (QUT) Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srdjan","family":"Djurovic","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics Oslo University Hospital Oslo Norway"},{"name":"NORMENT, Department of Clinical Science University of Bergen Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne L.","family":"Doherty","sequence":"additional","affiliation":[{"name":"MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences Cardiff University Cardiff United Kingdom"},{"name":"Cardiff University Brain Research Imaging Centre (CUBRIC) Cardiff United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Donohoe","sequence":"additional","affiliation":[{"name":"Center for Neuroimaging, Genetics and Genomics School of Psychology, NUI Galway Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Draganski","sequence":"additional","affiliation":[{"name":"LREN, Centre for Research in Neuroscience, Department of Neuroscience University Hospital Lausanne and University Lausanne Lausanne Switzerland"},{"name":"Neurology Department Max\u2010Planck Institute for Human Brain and Cognitive Sciences Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney A.","family":"Durdle","sequence":"additional","affiliation":[{"name":"MIND Institute and Department of Psychiatry and Behavioral Sciences University of California Davis Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Ehrlich","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neurosciences Faculty of Medicine, TU Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverly S.","family":"Emanuel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Espeseth","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Oslo Oslo Norway"},{"name":"Department of Psychology Bj\u00f8rknes College Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon E.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Language and Genetics Department Max Planck Institute for Psycholinguistics Nijmegen The Netherlands"},{"name":"Donders Institute for Brain, Cognition and Behaviour Radboud University Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Ge","sequence":"additional","affiliation":[{"name":"Psychiatric and Neurodevelopmental Genetics Unit Center for Genomic Medicine, Massachusetts General Hospital Boston Massachusetts USA"},{"name":"Department of Psychiatry, Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Glahn","sequence":"additional","affiliation":[{"name":"Tommy Fuss Center for Neuropsychiatric Disease Research Boston Children's Hospital Boston Massachusetts USA"},{"name":"Department of Psychiatry Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans J.","family":"Grabe","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE) Site Rostock\/Greifswald Greifswald Germany"},{"name":"Department of Psychiatry and Psychotherapy University Medicine Greifswald Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel E.","family":"Gur","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pennsylvania Philadelphia Pennsylvania USA"},{"name":"Youth Suicide Prevention, Intervention and Research Center Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris A.","family":"Gutman","sequence":"additional","affiliation":[{"name":"Medical Imaging Research Center, Department of Biomedical Engineering Illinois Institute of Technology Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Haavik","sequence":"additional","affiliation":[{"name":"Department of Biomedicine University of Bergen Bergen Norway"},{"name":"Division of Psychiatry Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asta K.","family":"H\u00e5berg","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology Trondheim Norway"},{"name":"Department of Radiology and Nuclear Medicine St. Olavs Hospital Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura A.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Biobehavioral Sciences University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryota","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Pathology of Mental Diseases National Institute of Mental Health, National Center of Neurology and Psychiatry Tokyo Japan"},{"name":"Department of Psychiatry Osaka University Graduate School of Medicine Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrek P.","family":"Hibar","sequence":"additional","affiliation":[{"name":"Personalized Healthcare Analytics Genentech, Inc. South San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avram J.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Department of Psychology Yale University New Haven Connecticut USA"},{"name":"Department of Psychiatry Yale University New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jouke\u2010Jan","family":"Hottenga","sequence":"additional","affiliation":[{"name":"Department of Biological Psychology Vrije Universiteit Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilleke E.","family":"Hulshoff Pol","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, UMC Utrecht Brain Center, University Medical Center Utrecht Utrecht University Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Jalbrzikowski","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma E. M.","family":"Knowles","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Psychiatry Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Kushan","sequence":"additional","affiliation":[{"name":"Semel Institute for Neuroscience and Human Behavior University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E. J.","family":"Linden","sequence":"additional","affiliation":[{"name":"School for Mental Health and Neuroscience Maastricht University Maastricht The Netherlands"},{"name":"Neuroscience and Mental Health Research Institute Cardiff University Cardiff United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Tri\u2010institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS) Georgia State, Georgia Tech, Emory Atlanta Georgia USA"},{"name":"Computer Science Georgia State University Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astri J.","family":"Lundervold","sequence":"additional","affiliation":[{"name":"Department of Biological and Medical Psychology University of Bergen Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Martin\u2010Brevet","sequence":"additional","affiliation":[{"name":"LREN, Centre for Research in Neuroscience, Department of Neuroscience University Hospital Lausanne and University Lausanne Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenia","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Mara\u00f1on, IsSGM, Universidad Complutense, School of Medicine Madrid Spain"},{"name":"Centro Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM) Madrid Spain"},{"name":"Facultad de Psicolog\u00eda Universidad Aut\u00f3noma de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen A.","family":"Mather","sequence":"additional","affiliation":[{"name":"Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, Faculty of Medicine University of New South Wales Sydney New South Wales Australia"},{"name":"Neuroscience Research Australia Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel R.","family":"Mathias","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Psychiatry Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna M.","family":"McDonald\u2010McGinn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA"},{"name":"Division of Human Genetics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"},{"name":"Division of Human Genetics and 22q and You Center Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan F.","family":"McRae","sequence":"additional","affiliation":[{"name":"Institute for Molecular Bioscience The University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Medland","sequence":"additional","affiliation":[{"name":"Psychiatric Genetics QIMR Berghofer Medical Research Institute Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torgeir","family":"Moberget","sequence":"additional","affiliation":[{"name":"Department of Psychology, Faculty of Social Sciences University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Modenato","sequence":"additional","affiliation":[{"name":"LREN, Centre for Research in Neuroscience, Department of Neuroscience University Hospital Lausanne and University Lausanne Lausanne Switzerland"},{"name":"University of Lausanne Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Monereo S\u00e1nchez","sequence":"additional","affiliation":[{"name":"School for Mental Health and Neuroscience Maastricht University Maastricht The Netherlands"},{"name":"Faculty of Health, Medicine and Life Sciences Maastricht University Maastricht The Netherlands"},{"name":"Department of Radiology and Nuclear Medicine Maastricht University Medical Center Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara A.","family":"Moreau","sequence":"additional","affiliation":[{"name":"Sainte Justine Hospital Research Center University of Montreal, Montreal QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.","family":"M\u00fchleisen","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Medicine (INM\u20101) Research Centre J\u00fclich J\u00fclich Germany"},{"name":"Cecile and Oskar Vogt Institute for Brain Research, Medical Faculty University Hospital D\u00fcsseldorf, Heinrich\u2010Heine\u2010University D\u00fcsseldorf D\u00fcsseldorf Germany"},{"name":"Department of Biomedicine University of Basel Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Paus","sequence":"additional","affiliation":[{"name":"Bloorview Research Institute Holland Bloorview Kids Rehabilitation Hospital Toronto Ontario Canada"},{"name":"Departments of Psychology and Psychiatry University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zdenka","family":"Pausova","sequence":"additional","affiliation":[{"name":"Translational Medicine, The Hospital for Sick Children Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Prieto","sequence":"additional","affiliation":[{"name":"Bioinformatics Service, Nucleus University of Salamanca Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjanibhargavi","family":"Ragothaman","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Oregon Health and Science University Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line S.","family":"Reinbold","sequence":"additional","affiliation":[{"name":"Department of Biomedicine University of Basel Basel Switzerland"},{"name":"Centre for Lifespan Changes in Brain and Cognition, Department of Psychology University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago","family":"Reis Marques","sequence":"additional","affiliation":[{"name":"Department of Psychosis Studies Institute of Psychiatry, Psychology and Neuroscience, King's College London London United Kingdom"},{"name":"Psychiatric Imaging Group, MRC London Institute of Medical Sciences (LMS), Hammersmith Hospital Imperial College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela M.","family":"Repetto","sequence":"additional","affiliation":[{"name":"Center for Genetics and Genomics Facultad de Medicina, Clinica Alemana Universidad del Desarrollo Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Reymond","sequence":"additional","affiliation":[{"name":"Center for Integrative Genomics University of Lausanne Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Roalf","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borja","family":"Rodriguez\u2010Herreros","sequence":"additional","affiliation":[{"name":"Service de Troubles du Spectre de l'Autisme Lausanne University Hospital Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"Rucker","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Institute of Psychiatry, Psychology and Neuroscience, King's College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perminder S.","family":"Sachdev","sequence":"additional","affiliation":[{"name":"Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, Faculty of Medicine University of New South Wales Sydney New South Wales Australia"},{"name":"Neuropsychiatric Institute The Prince of Wales Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Department of Radiology and Psychiatry University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R.","family":"Schofield","sequence":"additional","affiliation":[{"name":"Neuroscience Research Australia Sydney New South Wales Australia"},{"name":"School of Medical Sciences UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana I.","family":"Silva","sequence":"additional","affiliation":[{"name":"Neuroscience and Mental Health Research Institute Cardiff University Cardiff United Kingdom"},{"name":"School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences Maastricht University Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hreinn","family":"Stefansson","sequence":"additional","affiliation":[{"name":"Population Genomics, deCODE genetics\/Amgen Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan J.","family":"Stein","sequence":"additional","affiliation":[{"name":"SA MRC Unit on Risk &amp; Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute University of Cape Town Cape Town South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian K.","family":"Tamnes","sequence":"additional","affiliation":[{"name":"Norwegian Centre for Mental Disorders Research (NORMENT), Division of Mental Health and Addiction Oslo University Hospital and University of Oslo Oslo Norway"},{"name":"Department of Psychiatric Research Diakonhjemmet Hospital Oslo Norway"},{"name":"PROMENTA Research Center, Department of Psychology University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Tordesillas\u2010Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Centro Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM) Madrid Spain"},{"name":"Neuroimaging Unit, Technological Facilities Valdecilla Biomedical Research Institute (IDIVAL), Santander Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus O.","family":"Ulfarsson","sequence":"additional","affiliation":[{"name":"Population Genomics, deCODE genetics\/Amgen Reykjavik Iceland"},{"name":"Faculty of Electrical and Computer Engineering University of Iceland, Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariana","family":"Vajdi","sequence":"additional","affiliation":[{"name":"Semel Institute for Neuroscience and Human Behavior University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"van 't Ent","sequence":"additional","affiliation":[{"name":"Department of Biological Psychology Vrije Universiteit Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne B. M.","family":"van den Bree","sequence":"additional","affiliation":[{"name":"MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences Cardiff University Cardiff United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelos","family":"Vassos","sequence":"additional","affiliation":[{"name":"Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology &amp; Neuroscience, King's College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"V\u00e1zquez\u2010Bourgon","sequence":"additional","affiliation":[{"name":"Centro Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM) Madrid Spain"},{"name":"Department of Psychiatry Marqu\u00e9s de Valdecilla University Hospital, Valdecilla Biomedical Research Institute (IDIVAL) Santander Spain"},{"name":"School of Medicine University of Cantabria Santander Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fidel","family":"Vila\u2010Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Psychiatry The University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Bragi","family":"Walters","sequence":"additional","affiliation":[{"name":"Population Genomics, deCODE genetics\/Amgen Reykjavik Iceland"},{"name":"Faculty of Medicine University of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wen","sequence":"additional","affiliation":[{"name":"Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, Faculty of Medicine University of New South Wales Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars T.","family":"Westlye","sequence":"additional","affiliation":[{"name":"KG Jebsen Centre for Neurodevelopmental Disorders University of Oslo Oslo Norway"},{"name":"Department of Psychology University of Oslo Oslo Norway"},{"name":"NORMENT, Division of Mental Health and Addiction Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Wittfeld","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE) Site Rostock\/Greifswald Greifswald Germany"},{"name":"Department of Psychiatry and Psychotherapy University Medicine Greifswald Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine H.","family":"Zackai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA"},{"name":"Division of Human Genetics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1ri","family":"Stef\u00e1nsson","sequence":"additional","affiliation":[{"name":"Population Genomics, deCODE genetics\/Amgen Reykjavik Iceland"},{"name":"Faculty of Medicine University of Iceland Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastien","family":"Jacquemont","sequence":"additional","affiliation":[{"name":"Sainte Justine Hospital Research Center University of Montreal, Montreal QC Canada"},{"name":"Department of Pediatrics University of Montreal, Montreal QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Imaging Genetics Center Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California Marina del Rey California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie E.","family":"Bearden","sequence":"additional","affiliation":[{"name":"Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology University of California Los Angeles Los Angeles California USA"},{"name":"Center for Neurobehavioral Genetics University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole A.","family":"Andreassen","sequence":"additional","affiliation":[{"name":"Norwegian Centre for Mental Disorders Research (NORMENT), Division of Mental Health and Addiction Oslo University Hospital and University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the ENIGMA\u2010CNV Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the ENIGMA 22q11.2 Deletion Syndrome Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,21]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/thg.2014.86"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4398"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24331"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3554-12.2013"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.10.034"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1895"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291716000970"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2018.17040467"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2015.78"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2009.03.006"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2018.00080"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2016.16020201"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2018.00102"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005660"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.279"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.06.002"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.3646"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42256-019-0069-5"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.116155"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng2028"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2018.03.001"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.32390"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/378816"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23211"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(19)30123-3"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2019.19060583"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-020-0654-3"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms16024068"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2018-105477"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-160469"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2017.6"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291720002330"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1103-1"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.12.016"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.06.039"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.01.021"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0269-7"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2016.08.001"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.033"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.22587"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2012.129"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11203-y"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-017-1163-9"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-019-0440-7"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/461524"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2017.05.011"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl057"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.051"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00569-X"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-020-01485-4"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2019.09.023"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200395"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXG.0000000000000219"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M610314200"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00091.2008"},{"key":"e_1_2_13_57_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay6690"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.174"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-019-0344-8"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-019-0599-y"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay8833"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2017.161"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.107.080077"},{"key":"e_1_2_13_64_1","volume-title":"GeneReviews([R])","author":"Haldeman\u2010Englert C. R.","year":"1993"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.13146"},{"key":"e_1_2_13_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2593"},{"key":"e_1_2_13_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11405"},{"key":"e_1_2_13_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13624"},{"key":"e_1_2_13_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14101"},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.227"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2017.08.017"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18367-y"},{"key":"e_1_2_13_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(17)30049-4"},{"key":"e_1_2_13_74_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.0039"},{"key":"e_1_2_13_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1416"},{"key":"e_1_2_13_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2689"},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10406"},{"key":"e_1_2_13_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.04.061"},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-015-9278-9"},{"key":"e_1_2_13_80_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2018-105879"},{"key":"e_1_2_13_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2017.170"},{"key":"e_1_2_13_82_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2018.301"},{"key":"e_1_2_13_83_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2019.0566"},{"key":"e_1_2_13_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2016.08.014"},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(14)00122-9"},{"key":"e_1_2_13_86_1","doi-asserted-by":"publisher","DOI":"10.1192\/apt.bp.113.012039"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2013.07.022"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.32441"},{"key":"e_1_2_13_89_1","doi-asserted-by":"crossref","unstructured":"Knol M. J. Poot R. A. Evans T. E. Satizabal C. L. Mishra A. van derAuwera S. \u2026Adams H. H. H.(2020).Genetic variants for head size share genes and pathways with cancer.bioRxiv 2020.2007.2015.191114. doi:https:\/\/doi.org\/10.1101\/2020.07.15.191114","DOI":"10.1101\/2020.07.15.191114"},{"key":"e_1_2_13_90_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23047"},{"key":"e_1_2_13_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24998"},{"key":"e_1_2_13_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00294-019-00980-0"},{"key":"e_1_2_13_93_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3759-16.2017"},{"key":"e_1_2_13_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2019.12.028"},{"key":"e_1_2_13_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15948-9"},{"key":"e_1_2_13_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2017.08.016"},{"key":"e_1_2_13_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2016.84"},{"key":"e_1_2_13_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2016.54"},{"key":"e_1_2_13_99_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw477"},{"key":"e_1_2_13_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00556-x"},{"key":"e_1_2_13_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.145"},{"key":"e_1_2_13_102_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.4845"},{"key":"e_1_2_13_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2015.12.023"},{"key":"e_1_2_13_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3725"},{"key":"e_1_2_13_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2015.5"},{"key":"e_1_2_13_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2018.02.1176"},{"key":"e_1_2_13_107_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.71"},{"key":"e_1_2_13_108_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031913"},{"issue":"1","key":"e_1_2_13_109_1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/hbm.25311","article-title":"Ten years of enhancing neuro\u2010imaging genetics through meta\u2010analysis: An overview from the ENIGMA genetics working group","volume":"43","author":"Medland S. E.","year":"2020","journal-title":"Human Brain Mapping: ENIGMA Consortium Special Issue"},{"key":"e_1_2_13_110_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0805384"},{"key":"e_1_2_13_111_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-311271"},{"key":"e_1_2_13_112_1","doi-asserted-by":"publisher","DOI":"10.1038\/s10038-018-0543-7"},{"key":"e_1_2_13_113_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18997-2"},{"key":"e_1_2_13_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.12.035"},{"key":"e_1_2_13_115_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291719001119"},{"key":"e_1_2_13_116_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13229-019-0284-2"},{"key":"e_1_2_13_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.07.031"},{"key":"e_1_2_13_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-018-0339-8"},{"key":"e_1_2_13_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-017-0011-8"},{"key":"e_1_2_13_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13353-017-0407-4"},{"key":"e_1_2_13_121_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-018-5292-7"},{"key":"e_1_2_13_122_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhy204"},{"key":"e_1_2_13_123_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000606"},{"key":"e_1_2_13_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1852"},{"key":"e_1_2_13_125_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31828b2cbb"},{"key":"e_1_2_13_126_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1366-14.2014"},{"key":"e_1_2_13_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(95)93934-P"},{"key":"e_1_2_13_128_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.113.131052"},{"key":"e_1_2_13_129_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5272-03.2004"},{"key":"e_1_2_13_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2012.164"},{"issue":"1","key":"e_1_2_13_131_1","first-page":"42","article-title":"Chromosomal microarrays: Understanding genetics of neurodevelopmental disorders and congenital anomalies","volume":"6","author":"Rosenfeld J. A.","year":"2017","journal-title":"Journal of Pediatric Genetics"},{"key":"e_1_2_13_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2012.6"},{"key":"e_1_2_13_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-019-0511-y"},{"key":"e_1_2_13_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.12.036"},{"key":"e_1_2_13_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(03)00354-4"},{"key":"e_1_2_13_136_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13595"},{"key":"e_1_2_13_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.69"},{"key":"e_1_2_13_138_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.13070864"},{"key":"e_1_2_13_139_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1098918"},{"key":"e_1_2_13_140_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genom.7.080505.115618"},{"key":"e_1_2_13_141_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1862"},{"key":"e_1_2_13_142_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.31147"},{"key":"e_1_2_13_143_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhx197"},{"key":"e_1_2_13_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2018.11.004"},{"key":"e_1_2_13_145_1","first-page":"1","article-title":"Population prevalence and inheritance pattern of recurrent CNVs associated with neurodevelopmental disorders in 12,252 newborns and their parents","volume":"29","author":"Smajlagi\u0107 D.","year":"2020","journal-title":"European Journal of Human Genetics"},{"key":"e_1_2_13_146_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24238"},{"key":"e_1_2_13_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.02.024"},{"key":"e_1_2_13_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.12.018"},{"key":"e_1_2_13_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-018-0118-1"},{"key":"e_1_2_13_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-021-01213-0"},{"key":"e_1_2_13_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-018-0007-0"},{"key":"e_1_2_13_152_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-019-0397-8"},{"key":"e_1_2_13_153_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-100708-204735"},{"key":"e_1_2_13_154_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12818"},{"key":"e_1_2_13_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2250"},{"key":"e_1_2_13_156_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.180893.114"},{"key":"e_1_2_13_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.02.002"},{"key":"e_1_2_13_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-018-0078-5"},{"key":"e_1_2_13_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.067"},{"key":"e_1_2_13_160_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2011.244"},{"key":"e_1_2_13_161_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.143"},{"key":"e_1_2_13_162_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-020-00423-2"},{"key":"e_1_2_13_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.116073"},{"key":"e_1_2_13_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-020-0705-1"},{"key":"e_1_2_13_165_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-013-9269-5"},{"key":"e_1_2_13_166_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2017.77"},{"key":"e_1_2_13_167_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2019.3779"},{"issue":"4","key":"e_1_2_13_168_1","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/ajmg.b.31055","article-title":"A co\u2010segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder","volume":"153","author":"Zwaag B.","year":"2010","journal-title":"American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics"},{"key":"e_1_2_13_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.63"},{"key":"e_1_2_13_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2018.04.023"},{"key":"e_1_2_13_171_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2017.17010100"},{"key":"e_1_2_13_172_1","doi-asserted-by":"publisher","DOI":"10.1159\/000431274"},{"key":"e_1_2_13_173_1","unstructured":"Villalon Reina J. Nir T. M. Jahanshad N. Kushan L. Bearden C. E. &Thompson P. M.(2019).Altered intracellular volume fraction and Neurite dispersion in people with chromosome 22q11.2 copy number variants. Paper presented at the Engineering in Medicine and Biology ConferenceBerlin Germany."},{"key":"e_1_2_13_174_1","unstructured":"Villalon Reina J. Nir T. M. Kushan L. Bearden C. E. &Thompson P. M.(2019).Myelin and G\u2010ratio imaging in 22q11.2 deletion syndrome: A pilot study. Paper presented at the SFN Chicago."},{"key":"e_1_2_13_175_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-019-0450-0"},{"key":"e_1_2_13_176_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.6861907"},{"key":"e_1_2_13_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1841"},{"key":"e_1_2_13_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-019-0355-y"},{"key":"e_1_2_13_179_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awx341"},{"key":"e_1_2_13_180_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-017-0498-x"},{"key":"e_1_2_13_181_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158036"},{"key":"e_1_2_13_182_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0090-3"}],"container-title":["Human Brain Mapping"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.25354","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hbm.25354","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.25354","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T18:03:56Z","timestamp":1697911436000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hbm.25354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,21]]},"references-count":181,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1002\/hbm.25354"],"URL":"https:\/\/doi.org\/10.1002\/hbm.25354","archive":["Portico"],"relation":{},"ISSN":["1065-9471","1097-0193"],"issn-type":[{"value":"1065-9471","type":"print"},{"value":"1097-0193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,21]]},"assertion":[{"value":"2020-08-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}