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Previous neuroimaging work is sparse and has not used functional connectivity paradigms to more fully explore the neural correlates of emotional difficulties. Fifty\u2010seven acutely unwell AN (AAN) women, 60 weight\u2010recovered AN (WR) women and 69 healthy control (HC) women categorised the gender of a series of emotional faces while undergoing Functional Magnetic Resonance Imaging. The mean age of the AAN group was 19.40 (2.83), WR 18.37 (3.59) and HC 19.37 (3.36). A whole brain and psychophysical interaction connectivity approach was used. Parameter estimates from significant clusters were extracted and correlated with clinical symptoms. Whilst no group level differences in whole brain activation were demonstrated, significant group level functional connectivity differences emerged. WR participants showed increased connectivity between the bilateral occipital face area and the cingulate, precentral gyri, superior, middle, medial and inferior frontal gyri compared to AAN and HC when viewing happy valenced faces. Eating disorder symptoms and parameter estimates were positively correlated. Our findings characterise the neural basis of social\u2013emotional processing in a large sample of individuals with AN.<\/jats:p>","DOI":"10.1002\/hbm.25417","type":"journal-article","created":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T09:23:48Z","timestamp":1616145828000},"page":"3077-3087","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The emotional face of anorexia nervosa: The neural correlates of emotional processing"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5372-3179","authenticated-orcid":false,"given":"Daniel","family":"Halls","sequence":"first","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Psychological Medicine, King's College London (KCL)  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Leslie","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Psychological Medicine, King's College London (KCL)  London UK"},{"name":"Centre for Contextual Behavioural Science University of Chester  Chester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenni","family":"Leppanen","sequence":"additional","affiliation":[{"name":"Centre for Neuroimaging Sciences King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicity","family":"Sedgewick","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Psychological Medicine, King's College London (KCL)  London UK"},{"name":"School of Education University of Bristol  Bristol UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Surguladze","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Psychological Medicine, King's College London (KCL)  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon","family":"Fonville","sequence":"additional","affiliation":[{"name":"Division of Brain Sciences Imperial College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Lang","sequence":"additional","affiliation":[{"name":"King's College London (KCL) Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Department of Psychology  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mima","family":"Simic","sequence":"additional","affiliation":[{"name":"South London and Maudsley NHS Foundation Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dasha","family":"Nicholls","sequence":"additional","affiliation":[{"name":"Division of Brain Sciences Imperial College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Williams","sequence":"additional","affiliation":[{"name":"Centre for Neuroimaging Sciences King's College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Tchanturia","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Psychological Medicine, King's College London (KCL)  London UK"},{"name":"South London and Maudsley NHS Foundation Trust  London UK"},{"name":"Psychology Department Illia State University  Tbilisi Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-016-0264-x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_7_4_1","unstructured":"Anaconda Software Distribution. 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