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Novel forms of brain imaging have been developed to assess patients postconcussion, including functional magnetic resonance imaging (fMRI), susceptibility\u2010weighted imaging (SWI), diffusion MRI (dMRI), and perfusion MRI [arterial spin labeling (ASL)], but results have been mixed with a more common utilization in the research environment and a slower integration into the clinical setting. In this review, the benefits and drawbacks of the methods are described: fMRI is an effective method in the diagnosis of concussion but it is expensive and time\u2010consuming making it difficult for regular use in everyday practice; SWI allows detection of microhemorrhages in acute and chronic phases of concussion; dMRI is primarily used for the detection of white matter abnormalities, especially axonal injury, specific for mTBI; and ASL is an alternative to the BOLD method with its ability to track cerebral blood flow alterations. Thus, the absence of a universal diagnostic neuroimaging method suggests a need for the adoption of a multimodal approach to the neuroimaging of mTBI. Taken together, these methods, with their underlying functional and structural features, can contribute from different angles to a deeper understanding of mTBI mechanisms such that a comprehensive diagnosis of mTBI becomes feasible for the clinician.<\/jats:p>","DOI":"10.1002\/hbm.25630","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T09:43:19Z","timestamp":1629798199000},"page":"5477-5494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Noninvasive magnetic resonance imaging techniques in mild traumatic brain injury research and diagnosis"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7035-3886","authenticated-orcid":false,"given":"Ekaterina","family":"Lunkova","sequence":"first","affiliation":[{"name":"Department of Neurology &amp; Neurosurgery McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4422-2225","authenticated-orcid":false,"given":"Guido I.","family":"Guberman","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp; Neurosurgery McGill University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Ptito","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp; Neurosurgery McGill University  Montreal Quebec Canada"},{"name":"Montreal Neurological Institute  Montreal Quebec Canada"},{"name":"Department of Psychology McGill University Health Centre  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeet Singh","family":"Saluja","sequence":"additional","affiliation":[{"name":"Department of Neurology &amp; Neurosurgery McGill University  Montreal Quebec Canada"},{"name":"McGill University Health Centre Research Institute  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-160207"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0000000000000065"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2020.105908"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2014.3547"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2018.12.018"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(02)01674-8"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2016.4634"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2013.3213"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-52910-7.00013-1"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2010.1712"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.782"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2013.04.023"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617704105146"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699052.2018.1540798"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617707070634"},{"key":"e_1_2_6_17_1","first-page":"61","volume-title":"Handbook of clinical neurology","author":"Buchbinder B. 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