{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T02:40:16Z","timestamp":1785465616037,"version":"3.56.0"},"reference-count":69,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T00:00:00Z","timestamp":1634947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DFG KI1286\/6\u20101"],"award-info":[{"award-number":["DFG KI1286\/6\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["BI1254\/8\u20101"],"award-info":[{"award-number":["BI1254\/8\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["pericles.pericles-gcp.literatumonline.com"],"crossmark-restriction":true},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human vision prioritizes emotional stimuli. This is reflected in stronger electrocortical activation in response to emotional than neutral stimuli, measurable on the surface of the head. Feedback projections from brain structures deep within the medial temporal lobes (mTLs), in particular the amygdala, are thought to give rise to this phenomenon, although causal evidence is rare. Given the many pathways involved in visual processing, the influence of mTL structures could be restricted to specific time windows. Therefore, we delineate the temporal dynamics of the impact of right mTL structures on affective picture processing, investigating event\u2010related potentials (ERPs) in 19 patients (10 female) with right mTL resections and 19 individually matched healthy participants, while they viewed negative and neutral scenes. Groups differed significantly at early\u2010 and mid\u2010latency processing stages. Patients with right mTL resection, unlike controls, showed no (P1: 90\u2013140\u2009ms) or marginal (N1: 170\u2013220\u2009ms) emotion modulation. At mid\u2010latency (early posterior negativity: 220\u2013370\u2009ms), emotion modulation over the ipsi\u2010resectional right hemisphere was smaller in patients than in controls, but groups did not differ over the left hemisphere. During late parietal positivities (400\u2013650\u2009ms and 650\u2013900\u2009ms), both groups had similar emotion modulation. Our results demonstrate that right mTL structures attenuate particularly early processing of affectively negative scenes. This is theoretically consistent with an initial amygdala\u2010dependent feedforward sweep in visual emotion processing whose absence is successively compensated. Findings specify the impact of right mTL structures on emotional picture processing and highlight the value of time\u2010resolved measures in affective neuroscience.<\/jats:p>","DOI":"10.1002\/hbm.25687","type":"journal-article","created":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T15:36:19Z","timestamp":1635003379000},"page":"787-798","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Right medial temporal lobe structures particularly impact early stages of affective picture processing"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2921-4622","authenticated-orcid":false,"given":"Malena","family":"Mielke","sequence":"first","affiliation":[{"name":"Department of Psychology Bielefeld University  Bielefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9994-0016","authenticated-orcid":false,"given":"Lea Marie","family":"Reisch","sequence":"additional","affiliation":[{"name":"Department of Psychology Bielefeld University  Bielefeld Germany"},{"name":"Medical School, Department of Epileptology (Krankenhaus Mara) Bielefeld University  Bielefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Mehlmann","sequence":"additional","affiliation":[{"name":"Department of Psychology Bielefeld University  Bielefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7054-5431","authenticated-orcid":false,"given":"Sebastian","family":"Schindler","sequence":"additional","affiliation":[{"name":"Institute of Medical Psychology and Systems Neuroscience University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian G.","family":"Bien","sequence":"additional","affiliation":[{"name":"Medical School, Department of Epileptology (Krankenhaus Mara) Bielefeld University  Bielefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4567-1997","authenticated-orcid":false,"given":"Johanna","family":"Kissler","sequence":"additional","affiliation":[{"name":"Department of Psychology Bielefeld University  Bielefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.15.4.516"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)01001-1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.14.4.526"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsw154"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(88)90013-9"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2575"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20037"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.04.180"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.112.1.155"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp255"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0511(99)00044-7"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2007.05.030"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.231499798"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0401-13.2013"},{"key":"e_1_2_8_16_1","volume-title":"Surgical treatment of the epilepsies","author":"Engel Jr J. V. N. P.","year":"1993"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.2009.00796.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-80054-1"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1411315112"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2011.12.005"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858418785342"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-32-10274.2003"},{"key":"e_1_2_8_23_1","volume-title":"BDI\u2010II. Beck\u2010depressions\u2010inventar. Revision. 2, Auflage","author":"Hautzinger M.","year":"2009"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.14849"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.12.093"},{"key":"e_1_2_8_26_1","volume-title":"IBM SPSS statistics for windows (version 25.0) [computer software]","author":"IBM Corp","year":"2017"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200203000-00002"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wnr.0000198437.59883.bb"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20521"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsm020"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2011.06.003"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2015.00051"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2012.10.011"},{"key":"e_1_2_8_34_1","unstructured":"Lang P. J. Bradley M. M. &Cuthbert B. N.(2008).International affective picture system (IAPS): Affective ratings of pictures and instruction manual."},{"key":"e_1_2_8_35_1","volume-title":"STAI. State\u2010trait\u2010angstinventar","author":"Laux L.","year":"1981"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.23.1.155"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2007.08.005"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.09.065"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3525-16.2017"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4324"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2014.00275"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/30976"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.4.1680"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2003.09.021"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2007.11.006"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2920"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/861705"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.09.025"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2012.02.007"},{"key":"e_1_2_8_50_1","unstructured":"Reisch L. M. Mehlmann A. Wegrzyn M. Woermann F. Kissler J. &Bien C.(in preparation).Effects of left and right medial temporal lobe resections on hemodynamic correlates of negative and neutral scene processing."},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.25128"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2012.05.002"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20921"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.10.011"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3278-09.2009"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(06)56002-9"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1037\/1528-3542.4.2.189"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2012.02.009"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_00067"},{"key":"e_1_2_8_60_1","first-page":"S71","article-title":"Effects of right temporal lobe resection on visual emotion processing: An fMRI study","volume":"55","author":"Stieghorst L. M.","year":"2018","journal-title":"Psychophysiology"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2012.06.006"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13415-013-0225-z"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0634-18.2018"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2007.09.093"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-8986.3720190"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2005.10.011"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1341"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0020242"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2015.01.002"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2014.00674"}],"container-title":["Human Brain Mapping"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.25687","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hbm.25687","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.25687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T11:29:05Z","timestamp":1701257345000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hbm.25687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,23]]},"references-count":69,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1002\/hbm.25687"],"URL":"https:\/\/doi.org\/10.1002\/hbm.25687","archive":["Portico"],"relation":{},"ISSN":["1065-9471","1097-0193"],"issn-type":[{"value":"1065-9471","type":"print"},{"value":"1097-0193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,23]]},"assertion":[{"value":"2021-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}