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All children underwent magnetic resonance imaging conventional sequence, 3D\u2010T1, and enhanced T2*\u2010weighted magnetic resonance angiography (ESWAN) sequence scanning. The iron content of brain regions was obtained through software postprocessing, and the iron content of brain regions of children with ADHD and healthy children was compared and analyzed to find out the characteristics of the iron content of brain regions of children with ADHD. The iron content in frontal lobe, globus pallidus, caudate nucleus, substantia nigra, putamen, and hippocampus of children with ADHD was lower than that of healthy children (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). There was no significant difference in the content of iron in the left and right brain regions of children with ADHD (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). The volume of frontal lobe and hippocampus of children with ADHD was lower than that of healthy children (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Iron content in brain areas such as globus pallidus, caudate nucleus, hippocampus, and putamen could distinguish children with ADHD (Area under curve [AUC]\u2009&gt;\u20090.5, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Quantitative susceptibility mapping showed decreased iron content in some brain regions of children with ADHD.<\/jats:p>","DOI":"10.1002\/hbm.25798","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T12:07:18Z","timestamp":1643803638000},"page":"2495-2502","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Quantitative susceptibility mapping shows lower brain iron content in children with attention\u2010deficit hyperactivity disorder"],"prefix":"10.1002","volume":"43","author":[{"given":"Shilong","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Radiology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics  Chongqing Chongqing 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