{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:50:39Z","timestamp":1787161839884,"version":"build-2736575974"},"reference-count":72,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81601467"],"award-info":[{"award-number":["81601467"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871327"],"award-info":[{"award-number":["81871327"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Numerous studies indicate altered static local and long\u2010range functional connectivity of multiple brain regions in schizophrenia patients with auditory verbal hallucinations (AVHs). However, the temporal dynamics of interhemispheric and intrahemispheric functional connectivity patterns remain unknown in schizophrenia patients with AVHs. We analyzed resting\u2010state functional magnetic resonance imaging data for drug\u2010na\u00efve first\u2010episode schizophrenia patients, 50 with AVHs and 50 without AVH (NAVH), and 50 age\u2010 and sex\u2010matched healthy controls. Whole\u2010brain functional connectivity was decomposed into ipsilateral and contralateral parts, and sliding\u2010window analysis was used to calculate voxel\u2010wise interhemispheric and intrahemispheric dynamic functional connectivity density (dFCD). Finally, the correlation analysis was performed between abnormal dFCD variance and clinical measures in the AVH and NAVH groups. Compared with the NAVH group and healthy controls, the AVH group showed weaker interhemispheric dFCD variability in the left middle temporal gyrus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.01;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.001), as well as stronger interhemispheric dFCD variability in the right thalamus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.001;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.001) and right inferior temporal gyrus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.01;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.001) and stronger intrahemispheric dFCD variability in the left inferior frontal gyrus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.001;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.01). Moreover, abnormal contralateral dFCD variability of the left middle temporal gyrus correlated with the severity of AVHs in the AVH group (\n                    <jats:italic>r<\/jats:italic>\n                    \u00a0=\u00a0\u2212.319,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a0.024). The findings demonstrate that abnormal temporal variability of interhemispheric and intrahemispheric dFCD in schizophrenia patients with AVHs mainly focus on the temporal and frontal cortices and thalamus that are pivotal components of auditory and language pathways.\n                  <\/jats:p>","DOI":"10.1002\/hbm.25958","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T03:12:47Z","timestamp":1653448367000},"page":"4347-4358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Abnormal interhemispheric and intrahemispheric functional connectivity dynamics in drug\u2010na\u00efve first\u2010episode schizophrenia patients with auditory verbal hallucinations"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4264-6374","authenticated-orcid":false,"given":"Yarui","family":"Wei","sequence":"first","affiliation":[{"name":"Department of Magnetic 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