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We used a paradigm of virtual obedience to authority, in which an experimenter ordered a volunteer to press a handheld button to initiate actions that carried different consequences, including harming or helping others. In this study, we scanned the brain with functional neuroimaging and applied transcranial direct current stimulation (tDCS) to modulate the activation of the right temporoparietal junction (rTPJ) in healthy volunteers in a single\u2010blinded, sham\u2010controlled, crossover trial with anodal, cathodal, and sham stimulation. We observed that cathodal stimulation, compared to anodal and sham stimulation, significantly reduced reaction times (RTs) to initiating harming actions. The effect of tDCS on the rTPJ, orbitofrontal cortex, and anterior cingulate cortex had opposite directions depending on coercive harming or helping actions. Cathodal tDCS\u2010induced changes in the strength of the functional connectivity between the rTPJ and amygdala predicted the effect of cathodal tDCS on harming RTs. The findings provide evidence supporting the rTPJ having a role in coercion\u2010induced changes in the sense of agency. Neuromodulation with tDCS might help in unveiling the power of authority and assisting in the emergence of prosocial behavior, thus shedding light on coping strategies against coercion beyond merely examining its effects.<\/jats:p>","DOI":"10.1002\/hbm.26037","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T07:06:02Z","timestamp":1659596762000},"page":"5605-5615","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Neuromodulation of the right temporoparietal junction alters amygdala functional connectivity to authority pressure"],"prefix":"10.1002","volume":"43","author":[{"given":"Yawei","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation National Yang Ming Chiao Tung University Hospital  Yilan Taiwan"},{"name":"Institute of Neuroscience and Brain Research Center National Yang Ming Chiao Tung University  Taipei Taiwan"},{"name":"Department of Education and Research Taipei City Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Chun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Physical Education National Taiwan University of Sport  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang\u2010Teng","family":"Fan","sequence":"additional","affiliation":[{"name":"Graduate Institute of Medicine Yuan Ze University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8050-6754","authenticated-orcid":false,"given":"Chenyi","family":"Chen","sequence":"additional","affiliation":[{"name":"Graduate Institute of Injury Prevention and Control, College of Public Health Taipei Medical University  Taipei Taiwan"},{"name":"Brain and Consciousness Research Center, Shuang\u2010Ho Hospital Taipei Medical University  New Taipei City Taiwan"},{"name":"Graduate Institute of Mind, Brain and Consciousness, College of Humanities and Social Sciences Taipei Medical University  Taipei Taiwan"},{"name":"Psychiatric Research Center, Wan Fang Hospital Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.04.091"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0079-17.2017"},{"key":"e_1_2_10_4_1","volume-title":"The origins of totalitarianism","author":"Arendt H.","year":"1951"},{"key":"e_1_2_10_5_1","volume-title":"Eichmann in Jerusalem: A report on the banality of evil","author":"Arendt H.","year":"1963"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.21009"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.09.019"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2015.12.067"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204027"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2020.117251"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18152-x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.159905"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2020.116732"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-94372-5"},{"key":"e_1_2_10_15_1","volume-title":"Conscience: The origins of moral intuition","author":"Churchland P. 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