{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T10:25:03Z","timestamp":1775557503675,"version":"3.50.1"},"reference-count":81,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T00:00:00Z","timestamp":1660089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2022NSFSC0808"],"award-info":[{"award-number":["2022NSFSC0808"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81701776"],"award-info":[{"award-number":["81701776"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Brain Mapping"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Repetitive transcranial magnetic stimulation (rTMS) has been used in the clinical treatment of Parkinson's disease (PD). Most of rTMS studies on PD used high\u2010frequency stimulation; however, excessive nonvoluntary movement may represent abnormally cortical excitability, which is likely to be suppressed by low\u2010frequency rTMS. Decreased neural activity in the basal ganglia on functional magnetic resonance imaging (fMRI) is a characteristic of PD. In the present study, we found that low\u2010frequency (1\u2009Hz) rTMS targeting individual finger\u2010tapping activation elevated the amplitude of local neural activity (percentage amplitude fluctuation, PerAF) in the putamen as well as the functional connectivity (FC) of the stimulation target and basal ganglia in healthy participants. These results provide evidence for our hypothesis that low\u2010frequency rTMS over the individual task activation site can modulate deep brain functions, and that FC might serve as a bridge transmitting the impact of rTMS to the deep brain regions. It suggested that a precisely localized individual task activation site can act as a target for low\u2010frequency rTMS when it is used as a therapeutic tool for PD.<\/jats:p>","DOI":"10.1002\/hbm.26045","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T12:29:16Z","timestamp":1660134556000},"page":"203-217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Low\u2010frequency <scp>rTMS<\/scp> targeting individual self\u2010initiated finger\u2010tapping task activation modulates the amplitude of local neural activity in the putamen"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4790-4827","authenticated-orcid":false,"given":"Jue","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Sports Medicine and Health Chengdu Sport University  Chengdu People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin\u2010Ping","family":"Deng","sequence":"additional","affiliation":[{"name":"Institutes of Psychological Sciences Hangzhou Normal University  Hangzhou People's Republic of China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments  Hangzhou People's Republic of China"},{"name":"Center for Cognition and Brain Disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun\u2010Song","family":"Hu","sequence":"additional","affiliation":[{"name":"Institutes of Psychological Sciences Hangzhou Normal University  Hangzhou People's Republic of China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments  Hangzhou People's Republic of China"},{"name":"Center for Cognition and Brain Disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Yue","sequence":"additional","affiliation":[{"name":"Institutes of Psychological Sciences Hangzhou Normal University  Hangzhou People's Republic of China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments  Hangzhou People's Republic of China"},{"name":"Center for Cognition and Brain Disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiu","family":"Ge","sequence":"additional","affiliation":[{"name":"Institutes of Psychological Sciences Hangzhou Normal University  Hangzhou People's Republic of China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments  Hangzhou People's Republic of China"},{"name":"Center for Cognition and Brain Disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Long","family":"Li","sequence":"additional","affiliation":[{"name":"Institutes of Psychological Sciences Hangzhou Normal University  Hangzhou People's Republic of China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments  Hangzhou People's Republic of China"},{"name":"Center for Cognition and Brain Disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7228-3383","authenticated-orcid":false,"given":"Zi\u2010Jian","family":"Feng","sequence":"additional","affiliation":[{"name":"Institutes of Psychological Sciences Hangzhou Normal University  Hangzhou People's Republic of China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments  Hangzhou People's Republic of China"},{"name":"Center for Cognition and Brain Disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(90)90107-L"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1088\/2057-1976\/aaf202"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.07.007"},{"key":"e_1_2_12_5_1","first-page":"469","volume-title":"Handbook of clinical neurology","author":"Benninger D. H.","year":"2013"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2018.05.012"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910340409"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2018.10.011"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.5.1539"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099745"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25904"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2020.05.033"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.211"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2018.05.021"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.0976"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.21024"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-017-0005-6"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22364"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1113103109"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt007"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhab380"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504136102"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20006"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2009.06671.x"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1993.4"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910350312"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22397"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2000.80.3.953"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.01.035"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0227021"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2019.05.008"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-181540"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-140489"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2013.05.007"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2560\/12\/4\/046014"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-140397"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.09.132"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64032-1.00037-0"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.05.021"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2004.05.025"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2015.1086994"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(00)01110-0"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.12.029"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2196195"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.03.004"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2019.10.009"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(99)00040-5"},{"key":"e_1_2_12_48_1","first-page":"89","article-title":"Neurobiology of basal ganglia and Tourette syndrome: Basal ganglia circuits and thalamocortical outputs","volume":"99","author":"Mink J. W.","year":"2006","journal-title":"Advances in Neurology"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0510-4"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.1.51"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.04.067"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.25.112701.142937"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.27.070203.144216"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199807000-00005"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320206"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2015.02.001"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2016.02.006"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/52\/10\/016"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/54\/12\/002"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2013.03.002"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2021.05.032"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(00)01065-9"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-15-j0003.2001"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.12.032"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.0978"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2015.04.005"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00186"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10548-019-00741-9"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/giy071"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1252900"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-017-0146-x"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3761-14.2015"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurt.2008.02.002"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20622"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068910"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2017.02266"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.03.004"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12021-016-9299-4"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1919"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.1.141"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2018.00054"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.09.037"}],"container-title":["Human Brain Mapping"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.26045","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hbm.26045","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hbm.26045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T04:01:48Z","timestamp":1692590508000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hbm.26045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,10]]},"references-count":81,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1002\/hbm.26045"],"URL":"https:\/\/doi.org\/10.1002\/hbm.26045","archive":["Portico"],"relation":{},"ISSN":["1065-9471","1097-0193"],"issn-type":[{"value":"1065-9471","type":"print"},{"value":"1097-0193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,10]]},"assertion":[{"value":"2022-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}