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Surprisingly, the VOTC of congenitally blind humans features category\u2010selectivity for auditory and haptic objects. Yet it has been unknown whether VOTC would show category\u2010selective visual responses if sight were restored in congenitally blind humans. Assuming competition for synaptic space during development, cross\u2010modal activation of VOTC as a consequence of congenital blindness might interfere with visual processing in sight\u2010recovery individuals. To test this hypothesis, we investigated adults who had experienced a transient phase of congenital blindness due to bilateral dense cataracts before their sight was restored by cataract\u2010removal surgery. In a functional magnetic resonance imaging (fMRI) study, participants watched movies of faces, scenes, body parts, and other objects in the visual condition, while in the auditory condition they listened to the corresponding sounds. The most prominent group difference was a reduced face\u2010selectivity in individuals with reversed congenital cataracts compared with age\u2010 and sex\u2010matched normally sighted individuals. In addition, a double dissociation was found: only sight recovery individuals demonstrated significant decoding accuracy of visual categories based on auditory category representations in VOTC, while only normally sighted individuals' VOTC decoded auditory categories based on visual category representations. The present results uncovered the neural mechanisms of previously observed face processing impairments in individuals with reversed congenital blindness. We suggest that lower face\u2010selectivity in the sight recovery group might arise from selective deficits in the cortical representation of the central visual field in lower\u2010tier visual areas. Additionally, we speculate that in higher\u2010order visual areas cross\u2010modal activity might facilitate\u2014rather than interfere\u2014with visual functional recovery after congenital blindness.<\/jats:p>","DOI":"10.1002\/hbm.70316","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T07:25:05Z","timestamp":1756106705000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Visual and Auditory Object Representations in Ventral Visual Cortex After Restoring Sight in Humans"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8208-1761","authenticated-orcid":false,"given":"Katarzyna","family":"R\u0105czy","sequence":"first","affiliation":[{"name":"Biological Psychology and Neuropsychology University of Hamburg  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madita","family":"Linke","sequence":"additional","affiliation":[{"name":"Biological Psychology and Neuropsychology University of Hamburg  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Job","family":"van den Hurk","sequence":"additional","affiliation":[{"name":"Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience Maastricht University  Maastricht the Netherlands"},{"name":"Scannexus, Maastricht University  Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin","family":"Heitmann","sequence":"additional","affiliation":[{"name":"Biological Psychology and Neuropsychology University of Hamburg  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J. 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