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Previous research has not examined how the age at which trauma occurs influences associated behavioral and neural abnormalities. In this study, 76 adult participants (60.5% women) diagnosed with PTSD were categorized into three age\u2010matched groups based on the age at trauma onset: childhood, adolescence, and adulthood. Forty\u2010five healthy adults served as a control group. All participants engaged in the Shifted Attention Emotion Appraisal Task (SEAT) while undergoing functional magnetic resonance imaging (fMRI). Our findings reveal that both the childhood and adulthood trauma groups showed significantly greater activation in the left thalamus, left frontal gyrus, and Brodmann Area 48 compared to the adolescent trauma group. Additionally, the childhood trauma group exhibited higher activation in the left inferior frontal gyrus than the adolescent group and greater activation in the left pregenual anterior cingulate cortex compared to the adulthood trauma group. 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