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This study employed a sliding\u2010window approach to construct dynamic functional connectivity and investigated sex similarities and differences in modular variability (nodal level), edge variability (edge level), and state variability (brain state level) in brain connectomes among individuals with and without ASD. Ninety\u2010eight autistic individuals (49 female, 49 male; full\u2010scale IQ \u2265\u200970) and 98 typically developing individuals (TD; 49 female, 49 male), matched on sex, age, and full\u2010scale IQ, were selected from the Autism Brain Imaging Data Exchange (ABIDE). Results showed that both autistic males and females exhibited reduced modular variability in the left middle frontal gyrus and diminished edge variability in the functional connectivity between the right olfactory cortex and the right paracentral lobule, compared to their TD peers. Notably, autistic individuals manifested a sex\u2010opposite shift in the edge variability of functional connectivity between the left amygdala and the right anterior cingulate and paracingulate gyri. Furthermore, greater autistic symptom severity was associated with reduced maintenance of a high\u2010connectivity brain state characterized by functional competition between the frontal cortex and sensory\u2010perceptual or subcortical regions. These findings reveal both shared and sex\u2010differentiated alterations in connectome dynamics in ASD, with the sex\u2010specific patterns aligning with the gender incoherence model. Understanding these dynamic features may inform more individualized and sex\u2010sensitive educational and social support for individuals with ASD.<\/jats:p>","DOI":"10.1002\/hbm.70423","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T10:16:03Z","timestamp":1765534563000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sex Similarities and Differences in Brain Dynamic Functional Connectivity Among Individuals With and Without Autism Spectrum Disorders"],"prefix":"10.1002","volume":"46","author":[{"given":"Xue'er","family":"Ma","sequence":"first","affiliation":[{"name":"Shaanxi Provincial Key Research Center of Child Mental and Behavioral Health School of Psychology, Shaanxi Normal University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew K.","family":"Belmonte","sequence":"additional","affiliation":[{"name":"The Com DEALL Trust  Bangalore 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