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However, the causal role of beta synchrony in motor inhibition remains unclear. In this study, we employed dual\u2010site transcranial alternating current stimulation (tACS) targeting the right inferior frontal gyrus (rIFG) and left primary motor cortex (lM1) to directly manipulate phase relationships in the beta band and assess their effects on both functional connectivity and motor inhibition. Fifty\u2010two healthy participants received in\u2010phase, anti\u2010phase, and sham stimulation while performing a stop\u2010signal task. Connectivity between rIFG and lM1 increased following in\u2010phase stimulation and decreased after anti\u2010phase stimulation. No significant group\u2010level effects on stop\u2010signal task performance were observed. Exploratory \u0394\u2010\u0394 correlations indicated that individuals with larger connectivity increases during in\u2010phase stimulation tended to show greater improvements in inhibitory performance, whereas greater connectivity decreases during anti\u2010phase stimulation were associated with faster go responses. Crucially, ANCOVA analyses revealed significant stimulation\u2010dependent changes in the slope of the connectivity\u2010behavior relationship, demonstrating that tACS altered how beta synchrony predicted inhibitory and motor performance despite unchanged mean behavior. These findings suggest that dual\u2010site beta\u2010tACS can bidirectionally modulate rIFG\u2010M1 connectivity in a phase\u2010dependent manner and selectively alter how beta synchrony predicts stopping and motor execution. This mechanistic insight may inform future research exploring dual\u2010site beta\u2010tACS as a tool to probe or potentially normalize inhibitory network dynamics in disorders characterized by impaired inhibition.<\/jats:p>","DOI":"10.1002\/hbm.70470","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T06:57:07Z","timestamp":1771225027000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Phase\u2010Specific Dual\u2010Site Beta Transcranial Alternating Current Stimulation Differentially Influences Functional Connectivity Associated With Motor Inhibition Performance"],"prefix":"10.1002","volume":"47","author":[{"given":"Tingting","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Cognitive Neuroscience Faculty of Psychology and Neuroscience, Maastricht University  Maastricht the Netherlands"},{"name":"Maastricht Brain Imaging Centre (MBIC), Maastricht University 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