{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:37:10Z","timestamp":1787168230247,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Care Science"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To evaluate the feasibility and safety of a novel cable\u2010transmitted magnetically controlled capsule endoscopy (CT\u2010MCE) system for upper gastrointestinal examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty\u2010six participants (19 healthy volunteers and seven patients with gastrointestinal symptoms) willing to undergo upper gastrointestinal endoscopy were recruited. Each participant underwent CT\u2010MCE followed by conventional gastroscopy within 24\u2009h. Maneuverability and visibility of the CT\u2010MCE capsule in the upper gastrointestinal tract, adverse events, and discomfort during the procedure were evaluated. The sensitivity and specificity of CT\u2010MCE for diagnosing upper gastrointestinal lesions were evaluated using conventional gastroscopy findings as the standard.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Maneuverability was graded as \u201cgood\u201d for all segments of the esophagus. The percentage of participants in which maneuverability was good according to gastric region was as follows: cardia (100.00%), pylorus (96.15%), angulus (92.31%), antrum (88.46%), fundus (84.62%), and body (73.08%). In the duodenal bulb and descending duodenum, it was good in only 20.83% and 16.67% of participants, respectively. Visibility was graded as \u201cexcellent\u201d or \u201cgood\u201d in the esophagus, Z line, and duodenal bulb in all participants; excellent\/good visibility was achieved in the stomach and descending duodenum in 96.15% and 79.17% of participants, respectively. Forty\u2010one lesions were detected overall. The sensitivity and specificity of CT\u2010MCE in diagnosing upper gastrointestinal lesions were 85.00% and 98.15%, respectively. The CT\u2010MCE capsule was successfully removed through the mouth in all participants. No serious adverse events or capsule retention occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CT\u2010MCE showed good feasibility and safety for upper gastrointestinal examination. The system was effective in examining the esophagus and stomach with no risk of capsule retention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hcs2.70010","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T10:15:08Z","timestamp":1743416108000},"page":"94-102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility and Safety of a Novel Cable\u2010Transmitted Magnetically Controlled Capsule Endoscopy System for Upper Gastrointestinal Examination"],"prefix":"10.1002","volume":"4","author":[{"given":"Ke","family":"Meng","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Medical Center of Chinese PLA General Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Medical Center of Chinese PLA General Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Medical Center of Chinese PLA General Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology The First Medical Center of Chinese PLA General Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingshuang","family":"Yan","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanzhou","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University Tianjin 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