{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:31:08Z","timestamp":1786505468512,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012325","name":"National Office for Philosophy and Social Sciences","doi-asserted-by":"publisher","award":["17ZDA121"],"award-info":[{"award-number":["17ZDA121"]}],"id":[{"id":"10.13039\/501100012325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Care Science"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The medical expenses of cancer patients have been rising worldwide, and the current payment system based on diagnosis\u2010related groups is limited in reflecting the actual burden at the patient level. We aimed to develop a prediction model for reasonably high cost of hospitalization, taking gastric cancer (GC) patients undergoing surgery as an example.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this real\u2010world patient cohort study, we collected clinical data from 3981 GC surgery inpatients in a tertiary hospital in Beijing, China. Reasonably high cost was defined as exceeding the 75th percentile of the hospitalization costs. The final model for reasonably high cost was derived based on univariate and multivariate unconditional logistic regression, with predictors selected according to the Akaike information criterion. Model performance was evaluated in terms of discrimination and calibration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The final model consisted of 13 predictors, with the area under the receiver operating characteristics curve of 0.718 (95% confidence interval: 0.700\u20130.736). Leave\u2010one\u2010out cross\u2010validation generated an area under the receiver operating characteristics curve of 0.708 (95% confidence interval: 0.690\u20130.727). No significant differences in model discrimination were detected among the subgroups stratified by gender, age, N stage, surgical method, and admission year. The calibration plot showed good agreement between predicted probability and observed frequency of reasonably high cost.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our prediction tool for reasonably high cost of GC surgery patients has demonstrated good performance. The combined use of diagnosis\u2010related groups payment and reasonably high cost assessment is expected to promote individualization and precision in medical cost control and ensure rational, efficient, and equitable provision of medical services.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hcs2.70078","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T09:20:27Z","timestamp":1779182427000},"page":"341-352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Personalized Precision in Healthcare Payment Systems: Insights From a Real\u2010World Cancer Patients Cohort Study"],"prefix":"10.1002","volume":"5","author":[{"given":"Kan","family":"Xue","sequence":"first","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Gastrointestinal Cancer Center Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7294-3193","authenticated-orcid":false,"given":"Hongrui","family":"Tian","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education\/Beijing), Department of Genetics Peking University Cancer Hospital &amp; Institute Beijing China"},{"name":"Clinical Research Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine Tsinghua University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Endoscopy Center Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinkui","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Gastrointestinal Cancer Center Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Shan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Gastrointestinal Cancer Center Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yansui","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute for Hospital Management Tsinghua University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5659-0527","authenticated-orcid":false,"given":"Miao","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute for Hospital Management Tsinghua University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4444-7950","authenticated-orcid":false,"given":"Zhonghu","family":"He","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Molecular Oncology, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Genetics Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5580-4979","authenticated-orcid":false,"given":"Ziyu","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Gastrointestinal Cancer Center Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiafu","family":"Ji","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Gastrointestinal Cancer Center Peking University Cancer Hospital &amp; Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.21147\/j.issn.1000-9604.2021.05.09"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djq495"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(24)00072-X"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-020-4957-5"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.21037\/hbsn-2020-8"},{"issue":"2","key":"e_1_2_13_8_1","first-page":"1","article-title":"Case Mix Definition by Diagnosis\u2010Related Groups","volume":"18","author":"Fetter R. 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