{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:54:19Z","timestamp":1791266059870,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Care Science"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence of the longitudinal relationship between anxiety, depression, and post\u2010traumatic stress disorder (PTSD) is not uniform. This study aimed to explore the dynamic changes, independent factors, and bidirectional predictive relationships of anxiety, depression, and PTSD among medical staff.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study conducted a longitudinal follow\u2010up with two time points, 6 months apart, to collect medical staff's psychological data. Generalized linear mixed model and cross\u2010lagged model were used to identify independent factors of anxiety, depression, and PTSD among medical staff and explore longitudinal predictive relationships in main variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 2650 medical staff completed both baseline and follow\u2010up surveys, with a follow\u2010up response rate of 96.3%. From the first phase of the survey (T1) to the second phase of the survey (T2), the prevalence of anxiety (28.9% at T1 and 34.5% at T2), depression (19.4% and 26.7%), and PTSD (6.1% and 13.1%) among medical staff showed an upward trend. Occupational exposure, sleep quality, and experiencing traumatic life events were identified as independent factors associated with psychological disorders among medical staff. In addition, from T1 to T2, PTSD predicted anxiety and depression, and depression predicted PTSD and anxiety. However, anxiety could not predict depression and PTSD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of anxiety, depression, and PTSD among medical staff was higher and showed an upward trend. It is recommended to conduct early screening and intervention for medical staff's mental health problems, while paying close attention to the comprehensive management and intervention of these symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hcs2.70101","type":"journal-article","created":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:29:10Z","timestamp":1789288150000},"page":"404-414","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Study on Post\u2010Traumatic Stress Disorder, Anxiety, and Depression Among Medical Staff in China"],"prefix":"10.1002","volume":"5","author":[{"given":"Zongju","family":"Chen","sequence":"first","affiliation":[{"name":"School of Nursing, Tongji Medical College, Huazhong University of Science and Technology Wuhan China"},{"name":"Department of Emergency Medicine Sichuan Academy of Medical Sciences &amp; Sichuan Provincial People's Hospital Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiting","family":"Cai","sequence":"additional","affiliation":[{"name":"School of Nursing, Tongji Medical College, Huazhong University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Social Medicine and Health Management School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Nursing The Central Hospital of Wuhan Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Fei","sequence":"additional","affiliation":[{"name":"School of Nursing, Yangtze University Medical School Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wen","sequence":"additional","affiliation":[{"name":"School of Nursing, Tongji Medical College, Huazhong University of Science and Technology Wuhan China"},{"name":"Department of Orthodontics West China Hospital of Stomatology, Sichuan University Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Taihe Hospital, Hubei University of Medicine Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Nursing, Tongji Medical College, Huazhong University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Department of Cardiology Taihe Hospital, Hubei University of Medicine Shiyan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center, Renmin Hospital of Wuhan University &amp; Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1486-9781","authenticated-orcid":false,"given":"Li","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Neurology Renmin Hospital of Wuhan University &amp; Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4300-7977","authenticated-orcid":false,"given":"Wenning","family":"Fu","sequence":"additional","affiliation":[{"name":"School of Nursing, Tongji Medical College, Huazhong University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1744133116000128"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2019.11.24569"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1524838018774429"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/RMHP.S512458"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-025-07019-4"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(20)30047-X"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(20)30073-0"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2021.2013433"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000513733"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-021-01227-x"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/gpsych-2020-100344"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2024.1323111"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2022.104272"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1359104518822672"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beth.2022.08.001"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2020.20030305"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370204701003"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/bul0000111"},{"key":"e_1_2_13_20_1","unstructured":"World Health Organization \u201cInternational Classification of Diseases 11th Revision \u201d World Health Organization https:\/\/icd.who.int\/en."},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.22059"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1037\/1082-989x.1.1.16"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/00273171.2022.2163476"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0028599"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370705200405"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370905400504"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-062664"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04416.x"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100916"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-020-01990-x"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avb.2020.101381"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.22267"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702619858288"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.1018111"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1037\/tra0000455"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.12.119"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.696200"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/10615806.2010.517524"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10519-012-9535-0"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0084-3970(08)79089-3"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/21677026241301057"}],"container-title":["Health Care Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hcs2.70101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hcs2.70101","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hcs2.70101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:17:40Z","timestamp":1791263860000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hcs2.70101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,13]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/hcs2.70101"],"URL":"https:\/\/doi.org\/10.1002\/hcs2.70101","archive":["Portico"],"relation":{},"ISSN":["2771-1749","2771-1757"],"issn-type":[{"value":"2771-1749","type":"print"},{"value":"2771-1757","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,13]]},"assertion":[{"value":"2026-02-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}