{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T21:16:47Z","timestamp":1721078207341},"reference-count":44,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2011,9,2]],"date-time":"2011-09-02T00:00:00Z","timestamp":1314921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Health Economics"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Approximately 690\u2009000\u20131\u2009790\u2009000 <jats:italic>Salmonella<\/jats:italic> cases, 20\u2009000 hospitalizations, and 400 deaths occur in the USA annually, costing approximately $2.6bn. Existing models estimate morbidity, mortality, and cost solely from incidence. They do not estimate illness duration or use time as an independent cost predictor. Existing models may underestimate physician visits, hospitalizations, deaths, and associated costs. We developed a Markov chain Monte Carlo model to estimate illness duration, physician\/emergency room visits, inpatient hospitalizations, mortality, and resultant costs for a given <jats:italic>Salmonella<\/jats:italic> incidence. Interested parties include society, third\u2010party payers, health providers, federal, state and local governments, businesses, and individual patients and their families. The marginal approach estimates <jats:italic>individual<\/jats:italic> disease behavior for every patient, explicitly estimates disease duration and calculates separate time\u2010dependent costs. The aggregate approach is a Markov equivalent of the existing models; it assumes <jats:italic>average<\/jats:italic> disease behavior and cost for a given morbidity\/mortality. Transition probabilities were drawn from a meta\u2010analysis of 53 <jats:italic>Salmonella<\/jats:italic> studies. Both approaches were tested using the 1993 <jats:italic>Salmonella typhimurium<\/jats:italic> outbreak in Gideon, Missouri. This protocol can be applied to estimate morbidity, mortality and cost of specific outbreaks, provide better national <jats:italic>Salmonella<\/jats:italic> burden estimates, and estimate the benefits of reducing <jats:italic>Salmonella<\/jats:italic> risk. Copyright \u00a9 2011 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hec.1779","type":"journal-article","created":{"date-parts":[[2011,9,2]],"date-time":"2011-09-02T07:55:53Z","timestamp":1314950153000},"page":"1169-1182","source":"Crossref","is-referenced-by-count":3,"title":["A MARKOV MODEL TO ESTIMATE <i>SALMONELLA<\/i> MORBIDITY, MORTALITY, ILLNESS DURATION, AND COST"],"prefix":"10.1002","volume":"21","author":[{"given":"Robert L.","family":"Herrick","sequence":"first","affiliation":[{"name":"Department of Environmental Health University of Cincinnati College of Medicine  Cincinnati OH USA"},{"name":"Environmental Engineering Program, School of Energy, Environmental Biological and Medical Engineering University of Cincinnati  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven G.","family":"Buchberger","sequence":"additional","affiliation":[{"name":"Environmental Engineering Program, School of Energy, Environmental Biological and Medical Engineering University of Cincinnati  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Clark","sequence":"additional","affiliation":[{"name":"Environmental Engineering and Public Health Consultant  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Kupferle","sequence":"additional","affiliation":[{"name":"Environmental Engineering Program, School of Energy, Environmental Biological and Medical Engineering University of Cincinnati  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regan","family":"Murray","sequence":"additional","affiliation":[{"name":"Water Infrastructure Protection Division National Homeland Security Research Center U. S. Environmental Protection Agency  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Succop","sequence":"additional","affiliation":[{"name":"Department of Environmental Health University of Cincinnati College of Medicine  Cincinnati OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,2]]},"reference":[{"key":"e_1_2_6_1_2_1","unstructured":"AdhikariB AnguloFJ MeltzerM.2004.Economic Burden ofSalmonellaInfections in the United States. In:American Agricultural Economics Association Annual Meeting. 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