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However, the observed correlation may not be causal, as both methamphetamine use and risky sexual behavior could be driven by a third factor, such as a preference for risky behavior. We estimate the effect of methamphetamine use on risky sexual behavior using monthly data on syphilis diagnoses in California and quarterly data on syphilis, gonorrhea, and chlamydia diagnoses across all states. To circumvent possible endogeneity, we use a large exogenous supply shock in the US methamphetamine market that occurred in May 1995 and a later shock stemming from the Methamphetamine Control Act, which went into effect in October 1997. While the supply shocks had large negative effects on methamphetamine use, we find no evidence that they decreased syphilis, gonorrhea, or chlamydia rates. Our results have broad implications for public policies designed to decrease sexually transmitted infection rates. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hec.3140","type":"journal-article","created":{"date-parts":[[2014,12,29]],"date-time":"2014-12-29T14:39:03Z","timestamp":1419863943000},"page":"292-313","source":"Crossref","is-referenced-by-count":2,"title":["Crystal Clear? The Relationship Between Methamphetamine Use and Sexually Transmitted Infections"],"prefix":"10.1002","volume":"25","author":[{"given":"Hugo M.","family":"Mialon","sequence":"first","affiliation":[{"name":"Department of Economics Emory University  Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik T.","family":"Nesson","sequence":"additional","affiliation":[{"name":"Department of Economics Ball State University  Muncie IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C.","family":"Samuel","sequence":"additional","affiliation":[{"name":"Surveillance and Epidemiology Section, STD Control Branch California Department of Public Health  Richmond CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhealeco.2010.06.005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4076(82)90095-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2307\/2297968"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/338251a0"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1162\/003355304772839588"},{"issue":"4","key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/01.olq.0000194595.90487.ed","article-title":"Unsafe sexual behavior and correlates of risk in a probability sample of men who have sex with men in the era of highly active antiretroviral therapy","volume":"33","author":"Brewer DD","year":"2006","journal-title":"Sexually Transmitted Diseases"},{"key":"e_1_2_9_8_1","unstructured":"CaveD.2012.Mexico seizes record amount of methamphetamine.New York Times February 9 2012. 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