{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:26:34Z","timestamp":1768796794383,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2002,11,18]],"date-time":"2002-11-18T00:00:00Z","timestamp":1037577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2003,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>Most physicians are unaware of the juxtaoral organ (of Chievitz) and its clinical significance. The aim of this review is to draw attention to the clinical importance of this organ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Review and interpretation of the English and non\u2010English literature pertaining to the juxtaoral organ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>The juxtaoral organ is a small structure located within the soft tissue overlying the angle of the mandible in the buccotemporal space. It is composed of an epithelial parenchyma embedded in a highly organized connective tissue stroma rich in nerves and sensory receptors innervated by the buccal nerve. This metabolically active structure presumably serves as a mechanosensor in the lateral wall of the oral cavity. Needless surgical removal of this juxtaoral structure is therefore best avoided. In children, the normal organ may be discovered as a small mass in the cheeks, which may lead to extensive and unnecessary investigations. Hyperplasia of the parenchyma may occur, but carcinoma originating from this organ has not been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Awareness of this normal anatomic structure is important, because the finding of epithelial islands intimately admixed with nerves could be misinterpreted as perineural invasion by carcinoma. \u00a9 2002 Wiley Periodicals, Inc. Head Neck 25: 000\u2013000, 2003<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.10209","type":"journal-article","created":{"date-parts":[[2003,4,9]],"date-time":"2003-04-09T10:01:47Z","timestamp":1049882507000},"page":"400-405","source":"Crossref","is-referenced-by-count":35,"title":["Significance of the juxtaoral organ (of Chievitz)"],"prefix":"10.1002","volume":"25","author":[{"given":"Liron","family":"Pantanowitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karoly","family":"Balogh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,11,18]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(78)90385-7"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890040113"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(84)90261-5"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(79)90008-2"},{"key":"e_1_2_8_6_2","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/ajcp\/67.3.306","article-title":"Benign epithelial inclusions in pancreatic nerves","volume":"67","author":"Costa J","year":"1977","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_8_7_2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.5858\/2000-124-0465-BIEITB","article-title":"Benign intraneural epithelium in the breast","volume":"124","author":"Cerilli LA","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)45710-7"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/82.6.710"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/59.6.807"},{"key":"e_1_2_8_11_2","first-page":"401","article-title":"Beitr\u00e4ge zur Entwicklungsgeschichte der Speicheldr\u00fcsen","volume":"9","author":"Chievitz JH","year":"1885","journal-title":"Arch Anat Physiol Abt"},{"key":"e_1_2_8_12_2","first-page":"367","volume-title":"Histology for pathologists","author":"Balogh K","year":"1997"},{"key":"e_1_2_8_13_2","volume-title":"Juxtaoral organ (Chievitz's organ). 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