{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:34:23Z","timestamp":1790937263279,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2003,6,20]],"date-time":"2003-06-20T00:00:00Z","timestamp":1056067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2003,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction.<\/jats:title><jats:p>Limited information is available regarding surveillance patterns after head and neck cancer radiotherapy. We cataloged follow\u2010up for a specified patient cohort treated at three neighboring university, community, and Veterans Administration institutions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>One hundred fifteen patients were treated with curative intent between 1994\u20131998 with definitive or postoperative radiotherapy for newly diagnosed squamous cell carcinoma of the oral cavity, oropharynx, larynx, or hypopharynx. One hundred patients had continuous follow\u2010up at their treating institution and were included for analysis. Median follow\u2010up until disease recurrence or censorship was 28.5 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Median follow\u2010up frequency was 5.7 visits\/year and was highly variable. Although visit frequency correlated with disease stage and the presence of high\u2010risk disease features, this association was lost when patients with early recurrences were removed from analysis. Procedure and test utilization closely mirrored visit frequency, resulting in a wide range of estimated yearly charges ($0\u201315,668\/year; median, $1,772\/year). Actuarial 3\u2010year overall survival for the study group was 71%. Eighty\u2010six percent (19 of 22) of potentially salvageable locoregional failures were discovered secondary to symptomatic complaint rather than by test results. Disease failure, whether detected by symptom or testing, predicted for poor survival (22% at 24 months after recurrence).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>Postradiotherapy surveillance for head and neck cancer is inconsistently pursued. A proven correlation between intensive follow\u2010up and improved patient survival is lacking. Surveillance directed by patient symptoms should be investigated as an alternative approach. \u00a9 2003 Wiley Periodicals, Inc. Head Neck 25: 000\u2013000, 2003<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.10314","type":"journal-article","created":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T18:58:59Z","timestamp":1086116339000},"page":"990-999","source":"Crossref","is-referenced-by-count":101,"title":["Postradiotherapy surveillance practice for head and neck squamous cell carcinoma\u2014too much for too little?"],"prefix":"10.1002","volume":"25","author":[{"given":"David L.","family":"Schwartz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Jerry","family":"Barker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Chansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bevan","family":"Yueh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Raminfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Drago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Austin\u2010Seymour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George E.","family":"Laramore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen D.","family":"Hillel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest A.","family":"Weymuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent E.","family":"Wallner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,6,20]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301213280306"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1994.01880330022005"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(05)80068-1"},{"key":"e_1_2_5_5_2","first-page":"1358","article-title":"Multiple primary tumors: a survey of the literature and statistical study","volume":"51","author":"Warren S","year":"1932","journal-title":"Am J Cancer"},{"key":"e_1_2_5_6_2","unstructured":"National Comprehensive Cancer Network.The Complete Library of NCCN Oncology Practice Guidelines Version 1.2001."},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.5.564"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980515)82:10<1932::AID-CNCR17>3.0.CO;2-U"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00558-1"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70239-0"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.125.4.379"},{"key":"e_1_2_5_12_2","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1001\/jama.1994.03510440047031","article-title":"Impact of follow\u2010up testing on survival health\u2010related quality of life in breast cancer patients. 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