{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:12:19Z","timestamp":1792059139380,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,4,14]],"date-time":"2004-04-14T00:00:00Z","timestamp":1081900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>Transoral laser microsurgery is successfully performed in the treatment of primary laryngeal carcinomas. Few publications deal with the application in patients with recurrent glottic carcinomas after radiation failure. Our study aims to review our experience with transoral laser microsurgery in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Thirty\u2010four patients with early and advanced recurrent glottic carcinoma after full\u2010course radiotherapy (rT1, <jats:italic>n<\/jats:italic> = 11; rT2, <jats:italic>n<\/jats:italic> = 10; rT3, <jats:italic>n<\/jats:italic> = 10; rT4, <jats:italic>n<\/jats:italic> = 3) had CO<jats:sub>2<\/jats:sub> laser treatment with curative intent between 1987 and 1998.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Twenty\u2010four patients (71%) were cured with one or more laser procedures. In nine patients, recurrences could not be controlled by laser microsurgery: six patients underwent total laryngectomy and three palliative treatment. One patient received total laryngectomy because of chondronecrosis after laser treatment. With a median follow\u2010up interval of 38.6 months, the 3\u2010year and 5\u2010year disease\u2010specific survival was 86%. The overall 3\u2010year survival rate was 74%; the corresponding 5\u2010year survival rate was 53%. No major complications occurred. In three cases, temporary tracheostomy was needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>In early\u2010stage and advanced\u2010stage recurrent glottic carcinomas after radiotherapy, CO<jats:sub>2<\/jats:sub> laser treatment can successfully be used as a curative organ\u2010preserving procedure. Compared with salvage laryngectomy, results are superior with respect to preservation of laryngeal function. Great expertise is required, especially in resections of advanced\u2010stage recurrent carcinomas. \u00a9 2004 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>26:<\/jats:bold> 477\u2013484, 2004<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.20009","type":"journal-article","created":{"date-parts":[[2004,4,14]],"date-time":"2004-04-14T23:01:42Z","timestamp":1081983702000},"page":"477-484","source":"Crossref","is-referenced-by-count":95,"title":["Transoral carbon dioxide laser microsurgery for recurrent glottic carcinoma after radiotherapy"],"prefix":"10.1002","volume":"26","author":[{"given":"Wolfgang","family":"Steiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Vogt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Ambrosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Kron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,4,14]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910201)67:3<577::AID-CNCR2820670309>3.0.CO;2-W"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100094226"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100147681"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1994.01880330041008"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(05)80104-7"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1995.tb00037.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199703)19:2<116::AID-HED5>3.0.CO;2-7"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199810)20:7<630::AID-HED9>3.0.CO;2-K"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00333.x"},{"key":"e_1_2_6_11_2","volume-title":"Endoscopic laser surgery of the upper aerodigestive tract, with special emphasis on tumor surgery","author":"Steiner W","year":"2000"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0196-0709(93)90050-H"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s007610170103"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016489709124062"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198404000-00012"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198406000-00022"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459989110400611"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100129421"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0347(200008)22:5<520::AID-HED13>3.0.CO;2-K"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0347(200103)23:3<177::AID-HED1015>3.0.CO;2-8"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-69577-3_43"},{"key":"e_1_2_6_22_2","first-page":"33","volume-title":"TNM classification of malignant tumours","author":"Sobin LH","year":"1997"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1958.10501452"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348945106000313"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900409"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.20009","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.20009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T23:09:32Z","timestamp":1700262572000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.20009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4,14]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1002\/hed.20009"],"URL":"https:\/\/doi.org\/10.1002\/hed.20009","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,4,14]]}}}