{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T21:38:25Z","timestamp":1768081105702,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,2,15]],"date-time":"2005-02-15T00:00:00Z","timestamp":1108425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>Adenocarcinomas of the sinonasal cavity are unusual tumors with variable clinical courses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>We conducted a retrospective chart review between 1980 and 2001.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Twenty\u2010four patients (17 men) with sinonasal adenocarcinoma were identified. Nasal obstruction was the most common presenting symptom (75%), and the nose was the most common site of involvement (83%). Eleven tumors (46%) were high grade (grade 3 or 4). Twenty\u2010three patients (95%) underwent an attempt at surgical excision with tumor recurrence or residual disease in seven. Age and tumor grade were associated with overall survival, and tumor grade and intracranial extension were associated with death from disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>Presentation and treatment for nasal adenocarcinoma varies widely. Some low\u2010grade variants of nasal adenocarcinomas seem to be associated with a more favorable prognosis and, depending on the extent of the tumor, can be treated with less\u2010aggressive therapy. \u00a9 2005 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic> <jats:bold>27:<\/jats:bold> XXX\u2013XXX, 2005.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.20168","type":"journal-article","created":{"date-parts":[[2005,2,16]],"date-time":"2005-02-16T02:17:04Z","timestamp":1108520224000},"page":"370-375","source":"Crossref","is-referenced-by-count":63,"title":["Adenocarcinoma of the nose and paranasal sinuses: A retrospective study of diagnosis, histologic characteristics, and outcomes in 24 patients"],"prefix":"10.1002","volume":"27","author":[{"given":"Laura J.","family":"Orvidas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean E.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy L.","family":"Weaver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Bagniewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerry D.","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890060310"},{"key":"e_1_2_6_3_2","first-page":"77","volume-title":"Tumors of the head and neck: clinical and pathologic considerations","author":"Batsakis JG","year":"1979"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890020103"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/02841869709100731"},{"key":"e_1_2_6_6_2","first-page":"222","article-title":"Adenocarcinoma of the nose and paranasal sinuses in shoemakers and woodworkers in the province of Florence, Italy (1963\u201377)","volume":"37","author":"Cecchi F","year":"1980","journal-title":"Br J Ind Med"},{"key":"e_1_2_6_7_2","first-page":"12","article-title":"Cancer of the nasal cavity and paranasal sinuses: a series of 115 patients","volume":"36","author":"Svane\u2010Knudsen V","year":"1998","journal-title":"Rhinology"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1988.01860210062016"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910530209"},{"key":"e_1_2_6_10_2","first-page":"821","article-title":"Primary adenocarcinoma of the nasal cavity and paranasal sinuses","volume":"70","author":"Moran CA","year":"1991","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1963.00750010643012"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(99)90029-1"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/030089169307900310"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/019459988008800205","article-title":"\u201cColonic type\u201d adenocarcinoma of the nasal cavity and paranasal sinuses","volume":"88","author":"Salassa JR","year":"1980","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080606"},{"key":"e_1_2_6_16_2","first-page":"366","article-title":"Endoscopic diagnosis, treatment, and follow\u2010up of tumours of the nose and sinuses","volume":"23","author":"Blokmanis A","year":"1994","journal-title":"J Otolaryngol"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20011215)92:12<3012::AID-CNCR10131>3.0.CO;2-E"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880170406"}],"container-title":["Head &amp; 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