{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:43:43Z","timestamp":1768315423369,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,11,16]],"date-time":"2006-11-16T00:00:00Z","timestamp":1163635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>Parathyroid cryopreservation is essential in some cases of parathyroid surgery. The fate of autografted tissue after long\u2010term cryopreservation is not fully discussed in the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>The successful experience with the use of parathyroid tissues preserved for 21 months and 30 months is reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Both patients were women with renal hyperparathyroidism who underwent total parathyroidectomy without autotransplantation. Patient 1 was a 40\u2010year\u2010old woman. At 21 months of follow\u2010up, her parathyroid hormone (PTH) level was undetectable, and despite oral calcium supplements, she was hypocalcemic. Forty\u2010five cryopreserved fragments were thawed and implanted in her forearm. Calcium levels improved, and PTH steadily increased in both arms. PTH levels at 18 months after the autograft were 37.0 pg\/mL in the contralateral arm and 1150.0 pg\/mL in the implant arm. Patient 2 was a 44\u2010year\u2010old woman. After 30 months, her PTH was undetectable, and she underwent cryopreserved tissue implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>These cases show that parathyroid tissue may remain viable even after long\u2010term storage. \u00a9 2006 Wiley Periodicals, Inc. Head Neck, 2007<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.20506","type":"journal-article","created":{"date-parts":[[2006,11,17]],"date-time":"2006-11-17T14:59:49Z","timestamp":1163775589000},"page":"296-300","source":"Crossref","is-referenced-by-count":14,"title":["Successful implant of long\u2010term cryopreserved parathyroid glands after total parathyroidectomy"],"prefix":"10.1002","volume":"29","author":[{"given":"F\u00e1bio Luiz","family":"de Menezes Montenegro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melani Ribeiro","family":"Cust\u00f3dio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9rgio Samir","family":"Arap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciene Machado dos","family":"Reis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigueko","family":"Sonohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas Vieira","family":"Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanda","family":"Jorgetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An\u00f3i Castro","family":"Cordeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto Rosseti","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,8]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197902000-00002"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01665310"},{"key":"e_1_2_5_4_2","first-page":"86","article-title":"The successful transplantation of frozen parathyroid tissue in man","volume":"81","author":"Wells SA","year":"1977","journal-title":"Surgery"},{"key":"e_1_2_5_5_2","first-page":"49","article-title":"The transplanted parathyroid gland: evaluation of cryopreservation and other environmental factors which affect its function","volume":"75","author":"Wells SA","year":"1974","journal-title":"Surgery"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1982.01380290010003"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2005.09.029"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198010000-00003"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198803000-00014"},{"key":"e_1_2_5_10_2","first-page":"257","article-title":"The effect of cryopreservation on hormone secretion in vitro and morphology of human parathyroid tissue","volume":"99","author":"Wagner PK","year":"1986","journal-title":"Surgery"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(97)00156-6"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1999.tb01579.x"},{"key":"e_1_2_5_13_2","first-page":"111","article-title":"Resultados iniciales con criopreservaci\u00f3n de gl\u00e1ndulas paratiroides y potenciales aplicaciones","volume":"86","author":"Figari M","year":"2004","journal-title":"Rev Argent Cir"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900105"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90209-9"},{"key":"e_1_2_5_16_2","first-page":"1096","article-title":"The effect of cryopreservation on cell viability and hormone secretion in human parathyroid tissue","volume":"112","author":"Herrera MF","year":"1992","journal-title":"Surgery"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000043905.35268.86"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.06057"}],"container-title":["Head &amp; 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