{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T19:34:47Z","timestamp":1778700887282,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2008,1,28]],"date-time":"2008-01-28T00:00:00Z","timestamp":1201478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Anaplastic kinase\u20101 positive lymphoma (ALK\u20101) is a very rare but distinct pathologic entity. ALK\u20101 lymphoma tends to affect the bone marrow, skin, lungs, soft tissue, but very rarely the gastrointestinal tract.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We report a case of ALK\u20101 positive lymphoma presenting as a tracheoesophageal fistula. The clinical presentation, histopathology, and management outcome are all discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ALK\u20101 positive lymphoma of the upper aerodigestive involvement is extremely rare. An unusual presentation such as pharyngeal pouch with vocal cord palsy should suggest pathology. Histopathologic analysis can be difficult and immunohistochemical studies will aid are of paramount importance in the diagnosis and help in subsequent management and also act as prognostic indicators. \u00a9 2008 Wiley Periodicals, Inc. Head Neck, 2008<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.20774","type":"journal-article","created":{"date-parts":[[2008,1,28]],"date-time":"2008-01-28T18:22:36Z","timestamp":1201544556000},"page":"1264-1268","source":"Crossref","is-referenced-by-count":15,"title":["Anaplastic lymphoma of the cervical esophagus presenting as a tracheoesophageal fistula"],"prefix":"10.1002","volume":"30","author":[{"given":"Anil","family":"Joshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Fields","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricard","family":"Simo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,1,28]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"2697","article-title":"ALK\u20101+ Lymphoma: clinico\u2010pathological findings and outcome","volume":"8","author":"Falini B","year":"1999","journal-title":"Blood"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65629-5"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/299065a0"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1182\/blood.V89.4.1394","article-title":"Detection of anaplastic lymphoma kinase (ALK) and nuclear protein nucleophosmin (NPM)\u2010ALK protein in normal and neoplastic cells with the monoclonal antibody ALK1","volume":"89","author":"Pulford K","year":"1997","journal-title":"Blood"},{"key":"e_1_2_5_6_2","first-page":"3909","article-title":"The Non\u2010Hodgkin's Lymphoma Classification Project. 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