{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:49:58Z","timestamp":1762865398690},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:00:00Z","timestamp":1204848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Synovial sarcoma is an unusual neoplasm of mesenchymal derivation, which is uncommon in the head and neck sites. In the parotid gland, it is most likely to be misdiagnosed as a myoepithelial, primary mesenchymal, or metastatic neoplasm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We report a case of synovial sarcoma in a young woman who was seen with temporomandibular joint symptoms with a 10\u2010year history. A review of the literature was undertaken to highlight the radiologic and histologic features that help in diagnosis as well as the suggested therapeutic protocols most likely to ensure better survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Radiologic and histologic studies of the parotid mass led to a diagnosis of synovial sarcoma. A total parotidectomy was performed, and the individual remains tumor free at 36months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Review of the literature suggests an aggressive long\u2010term outcome for synovial sarcoma and advocates early diagnosis and radical surgical excision for a favorable prognosis. \u00a9 2008 Wiley Periodicals, Inc. Head Neck, 2008<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.20822","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T19:55:50Z","timestamp":1204919750000},"page":"1654-1659","source":"Crossref","is-referenced-by-count":15,"title":["Synovial sarcoma presenting as a parotid mass: Case report and review of literature"],"prefix":"10.1002","volume":"30","author":[{"given":"Amrita","family":"Jay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iain","family":"Hutchison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Piper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula M.","family":"Farthing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polly S.","family":"Richards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,3,7]]},"reference":[{"key":"e_1_2_4_2_2","first-page":"200","volume-title":"World Health Organization classification of tumours. Pathology and genetics of soft tissue and bone","author":"Fisher C","year":"2002"},{"key":"e_1_2_4_3_2","first-page":"1043","volume-title":"Soft tissue tumors","author":"Enzinger FM","year":"2001"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820715)50:2<269::AID-CNCR2820500217>3.0.CO;2-7"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2003.12.005"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(03)00209-9"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59980301392-5"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2003.10.022"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200211000-00013"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.anndiagpath.2004.04.007"},{"key":"e_1_2_4_11_2","first-page":"32","article-title":"Synovial sarcoma of the parotid gland. A case report with clinicopathological analysis and review of the literature","volume":"36","author":"Grayson W","year":"1998","journal-title":"S Afr J Surg"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459989210700504"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.109662"},{"key":"e_1_2_4_14_2","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1017\/S0022215100138617","article-title":"Tumours and pseudotumorous lesions of the temporomandibular joint: a diagnostic challenge","volume":"111","author":"Montmayeur FA","year":"1997","journal-title":"J Laryngol Otol"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1092-9134(98)80042-7"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197504)35:4<1243::AID-CNCR2820350432>3.0.CO;2-A"},{"key":"e_1_2_4_17_2","doi-asserted-by":"crossref","unstructured":"HirschRJ YousemDM LoevnerLA et al.Synovial sarcomas of the head and neck MR findings. Am J Roentgenol1997;169:1185\u20131188.","DOI":"10.2214\/ajr.169.4.9308488"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820715)50:2<345::AID-CNCR2820500231>3.0.CO;2-Y"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000326558"},{"key":"e_1_2_4_20_2","first-page":"167","article-title":"S100 protein reactivity in synovial sarcomas\u2014a potentially frequent diagnostic pitfall. Immunohistochemical analysis of 100 cases","volume":"4","author":"Guillou L","year":"1996","journal-title":"Appl Immunohistochem"},{"key":"e_1_2_4_21_2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/ajcp\/112.5.641","article-title":"Usefulness of cytokeratin subsets for distinguishing monophasic synovial sarcoma from malignant peripheral nerve sheath tumour","volume":"112","author":"Smith TA","year":"1999","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_4_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19981001)83:7<1292::AID-CNCR4>3.0.CO;2-L"},{"key":"e_1_2_4_23_2","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1002\/j.1460-2075.1995.tb07228.x","article-title":"Fusion of SYT to two genes, SSX1 and SSX2 encoding proteins with homology to the Kruppel associated box in human synovial sarcoma","volume":"10","author":"Crew AJ","year":"1995","journal-title":"EMBO J"},{"key":"e_1_2_4_24_2","first-page":"559","article-title":"Interphase fluorescence in situ hybridization and reverse transcriptase polymerase chain reaction as a diagnostic aid for synovial sarcoma","volume":"148","author":"Shipley J","year":"1996","journal-title":"Am J Pathol"},{"key":"e_1_2_4_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11840"},{"key":"e_1_2_4_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02893385"},{"key":"e_1_2_4_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810701215"},{"key":"e_1_2_4_28_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.22.3794"},{"key":"e_1_2_4_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949210100415"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.20822","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.20822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T05:06:06Z","timestamp":1700024766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.20822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,7]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1002\/hed.20822"],"URL":"https:\/\/doi.org\/10.1002\/hed.20822","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,7]]}}}