{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:50:56Z","timestamp":1762865456352},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,10,13]],"date-time":"2008-10-13T00:00:00Z","timestamp":1223856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sinonasal malignant fibrous histiocytoma (MFH) is rare.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010five patients were registered with a diagnosis of sinonasal MFH at our hospital in the past 30 years. Clinical data were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight tumors were primary MFH and 17 tumors were post\u2010irradiated MFH, located within the radiation field for previous nasopharyngeal carcinoma. Twenty\u2010one tumors originated from the maxillary sinus, 3 from the nasopharynx, and 1 from the nasal cavity. Twenty\u2010three patients underwent surgery but only 12 tumors were removed completely. The 5\u2010year overall and disease\u2010free survival rates were 25.1% and 21.5%, respectively. Multivariate analyses showed that previous radiation was the only adverse prognostic factor for disease\u2010free survival (<jats:italic>p<\/jats:italic> = .045). The 5\u2010year disease\u2010free survival rates of primary MFH and post\u2010irradiated MFH were 72.9% and 0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this series, post\u2010irradiated MFH was more common than primary MFH. The prognosis of post\u2010irradiated MFH is poor, whereas primary MFH is fair. \u00a9 2008 Wiley Periodicals, Inc. 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