{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T09:15:55Z","timestamp":1772010955239,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,11,20]],"date-time":"2008-11-20T00:00:00Z","timestamp":1227139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>Technetium 99m sestamibi scans have become a principal means of localizing parathyroid adenomas. Its accuracy and reliability has allowed for the proliferation of minimal access parathyroidectomy. Localizing interpretation of these scans often drives referral of hyperparathyroid patients for surgery. Interpretation of these scans may differ between nuclear medicine physicians and surgeons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>We reviewed patients (<jats:italic>N<\/jats:italic> = 65) with digital images from an academic medical center with the diagnosis of primary hyperparathyroidism. We assessed the willingness to define an adenoma's location, the interrater reliability, and the accuracy of technetium (Tc\u201099m) sestamibi read by a surgeon and a nuclear medicine physician.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>There was poor correlation between both readers for assessment of quality of images (<jats:italic>k<\/jats:italic> = 0.54, 0.07) but very good correlation for adenoma location (<jats:italic>k<\/jats:italic> = 0.81).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Both readers had good accuracy in predicting the location of the parathyroid adenoma. The surgeon was more likely to call a scan positive. \u00a9 2008 Wiley Periodicals, Inc. Head Neck, 2009<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.20982","type":"journal-article","created":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T05:02:20Z","timestamp":1227243740000},"page":"576-582","source":"Crossref","is-referenced-by-count":9,"title":["Accuracy and definitive interpretation of preoperative technetium 99m sestamibi imaging based on the discipline of the reader"],"prefix":"10.1002","volume":"31","author":[{"given":"Ayesha N.","family":"Khalid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher S.","family":"Hollenbeak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce W.","family":"Higginbotham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Brendan C.","family":"Stack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,11,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.10.005"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200009000-00005"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2004.02.016"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2004.02.002"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(99)80336-5"},{"key":"e_1_2_6_7_2","first-page":"639","article-title":"Prospective comparison of radionuclide, computed tomographic, sonographic, and magnetic resonance localization of parathyroid tumors","volume":"106","author":"Krubsack AJ","year":"1989","journal-title":"Surgery"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.05.001"},{"key":"e_1_2_6_9_2","first-page":"433","article-title":"Ultrasound\u2010guided unilateral neck exploration for sporadic primary hyperparathyroidism: is it worthwhile?","volume":"80","author":"Ammori BJ","year":"1998","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_6_10_2","first-page":"582","article-title":"Cost\u2010effectiveness of preoperative localization studies in primary hyperparathyroid disease","volume":"219","author":"Roe SM","year":"1994","journal-title":"Ann Surg"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90201-4"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.1.46"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mnm.0000168407.95508.dc"},{"key":"e_1_2_6_14_2","first-page":"1646","article-title":"Effect of mitochondrial and plasma membrane potentials on accumulation of hexakis (2\u2010methoxyisobutylisonitrile) technetium(I) in cultured mouse fibroblasts","volume":"31","author":"Chiu ML","year":"1990","journal-title":"J Nucl Med"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.6.493"},{"key":"e_1_2_6_16_2","first-page":"313","article-title":"Parathyroid imaging with technetium\u201099m\u2010sestamibi: preoperative localization and tissue uptake studies","volume":"33","author":"O'Doherty MJ","year":"1992","journal-title":"J Nucl Med"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03164759"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200303000-00032"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2004.02.010"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890160011002"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2004.02.019"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.20982","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.20982","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T19:34:17Z","timestamp":1699904057000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.20982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,20]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.1002\/hed.20982"],"URL":"https:\/\/doi.org\/10.1002\/hed.20982","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,20]]}}}