{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:34:43Z","timestamp":1787625283132,"version":"build-2736575974"},"reference-count":48,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,3,3]],"date-time":"2009-03-03T00:00:00Z","timestamp":1236038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>In patients with extensive soft tissue fibrosis requiring circumferential pharyngeal reconstruction following definitive radiotherapy and\/or chemotherapy, we take advantage of abundant omental progenitor factors in the tubed gastro\u2010omental free flap. This study reviews our experience with this flap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Review of 11 patients (median follow\u2010up, 2.8 years) undergoing total pharyngolaryngectomy following organ preservation protocols for recurrent squamous cell carcinoma (<jats:italic>n<\/jats:italic> = 9) and stricture (<jats:italic>n<\/jats:italic> = 2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Operative morbidity and mortality rates were 54% and 9%, respectively. One patient died following carotid rupture. Complications included: chyle leak (18%), pharyngocutaneous fistula (9%), and late stricture (27%). Ten patients (91%) achieved oral diet, and all 7 patients (100%) considered suitable for tracheoesophageal speech rehabilitation achieved functional speech. Seven patients remain alive without disease at a median of 41 months following surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>The gastro\u2010omental flap provides a viable option in high\u2010risk patients undergoing circumferential pharyngeal reconstruction. \u00a9 2009 Wiley Periodicals, Inc. Head Neck, 2009<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.21016","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T01:54:53Z","timestamp":1236131693000},"page":"655-663","source":"Crossref","is-referenced-by-count":31,"title":["Morbidity and functional outcomes following gastro\u2010omental free flap reconstruction of circumferential pharyngeal defects"],"prefix":"10.1002","volume":"31","author":[{"given":"Rajan S.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti A.","family":"Makitie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Gullane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Irish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph W.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,3]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20002"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880110206"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.1.44"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1995.01890020024006"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(05)70085-X"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.110617"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199903)21:2<131::AID-HED6>3.0.CO;2-F"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0347(200101)23:1<29::AID-HED5>3.0.CO;2-P"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880170103"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200304000-00003"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)30472-2"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31970-8"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/039139880703000203"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000191459.40059.fd"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199701)19:1<68::AID-HED13>3.0.CO;2-N"},{"key":"e_1_2_5_17_2","first-page":"847","article-title":"Tubed gastro\u2010omental free flap for pharyngoesophageal reconstruction","volume":"127","author":"Genden EM","year":"2001","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200308000-00002"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199011000-00012"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-004-0828-7"},{"key":"e_1_2_5_21_2","first-page":"202","article-title":"Therapeutic options for cancer of the hypopharynx and cervical oesophagus","volume":"84","author":"Bardini R","year":"1995","journal-title":"Ann Chir Gynaecol"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1994.01420280103013"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2001.00480.x"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930430107"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90146-5"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.136.10.1164"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199805)20:3<240::AID-HED9>3.0.CO;2-0"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-195902000-00002"},{"key":"e_1_2_5_29_2","first-page":"1012","article-title":"Free grafting and revascularization of intestine. 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