{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T17:06:01Z","timestamp":1783357561485,"version":"3.54.6"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2009,6,17]],"date-time":"2009-06-17T00:00:00Z","timestamp":1245196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>Significant morbidity is associated with management of anterior skull base neoplasms. The aim of this study was to evaluate the posttreatment patient's quality of life (QOL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>A retrospective chart review identified 27 patients. QOL tools included the Functional Assessment of Cancer Therapy\u2013Head &amp; Neck, Centre for Epidemiologic Studies Depression Scale (CES\u2010D), Atkinson Life Happiness Rating (ALHR), and Midface Dysfunction Scale (MDS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Postoperative radiotherapy and chemotherapy was required in 16 and 2 patients, respectively. The median FACT, ALHR, and CES\u2010D scores were 118 \u00b1 21, 9 \u00b1 2, and 17 \u00b1 8, respectively. Smell and nasal crusting disturbance was reported by 69% and 61%, respectively. CES\u2010D &gt; 16 and patients with recurrent disease correlated with a lower Total\u2010FACT score. Adjuvant radiotherapy correlated with a lower FACT\u2010H&amp;N score. Patient sex, marital\u2010status, pathology, surgical technique, or complication rate did not correlate with worse QOL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Anterior skull base neoplasms survivors have an overall acceptable QOL. Most complaints relate to MDS. Recurrence, adjuvant radiotherapy, and MDS had lower QOL scores. \u00a9 2009 Wiley Periodicals, Inc. 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