{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:15:11Z","timestamp":1774923311909,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2009,4,29]],"date-time":"2009-04-29T00:00:00Z","timestamp":1240963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title><jats:italic>Background.<\/jats:italic><\/jats:title><jats:p>Curative parathyroidectomy is associated with elevated levels of parathyroid hormone (PTH) with eucalcemia. This study sought to determine the frequency, clinical significance, and risk factors of this finding.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Methods.<\/jats:italic><\/jats:title><jats:p>Seventy\u2010six consecutive patients surgically treated for primary hyperparathyroidism due to a single parathyroid adenoma in 2006 to 2007 were monitored for 1 month postoperatively; those with elevated PTH levels (&gt;70 pg\/mL) were monitored for 18 months.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Results.<\/jats:italic><\/jats:title><jats:p>Nineteen patients (25%) had high postoperative PTH levels with normal calcium levels. Compared with the remaining patients, this group had a significantly higher average preoperative PTH level (224.89 vs 156.86 pg\/mL) and a lesser intraoperative decrease in PTH.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Conclusions.<\/jats:italic><\/jats:title><jats:p>About 25% of eucalcemic patients may have elevated PTH levels after parathyroidectomy. A high preoperative PTH level (&gt;225 pg\/mL) may predict a persistently high postoperative level. Evaluation of blood and urine calcium, bone density, and cardiac function should be considered in affected patients. Head Neck, 2009<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.21119","type":"journal-article","created":{"date-parts":[[2009,4,29]],"date-time":"2009-04-29T16:22:09Z","timestamp":1241022129000},"page":"1456-1460","source":"Crossref","is-referenced-by-count":23,"title":["Elevated parathyroid hormone levels after parathyroidectomy for primary hyperparathyroidism"],"prefix":"10.1002","volume":"31","author":[{"given":"Aviram","family":"Mizrachi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Gilat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gideon","family":"Bachar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Feinmesser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Shpitzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,4,29]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"898","article-title":"Parathyroid metabolism after operative treatment of hypercalcaemic (primary) hyperparathyroidism","volume":"102","author":"Irvin GL","year":"1987","journal-title":"Surgery"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(01)00664-X"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2007.01.025"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2004.04.003"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2004.12.009"},{"key":"e_1_2_5_7_2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/s00268-002-6600-5","article-title":"Patients with elevated serum parathyroid hormone levels after parathyroidectomy: showing signs of decreased peripheral parathyroid hormone sensitivity","volume":"27","author":"Nordenstr\u00f6m E","year":"2003","journal-title":"World J Surg"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.3.275"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002680010219"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2002.128479"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.9.1055"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200205000-00008"},{"key":"e_1_2_5_13_2","first-page":"1021","article-title":"Parathyroid hormone: before and after parathyroidectomy","volume":"100","author":"Duh QY","year":"1986","journal-title":"Surgery"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(96)80186-3"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7124-y"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.07.006"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-2802"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.07.010"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000007031"},{"key":"e_1_2_5_20_2","first-page":"391","article-title":"Minimally invasive parathyroidectomy for primary hyperparathyroidism: decreasing operative time and potential complications while improving cosmetic results","volume":"64","author":"Norman J","year":"1998","journal-title":"Am Surg"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20131"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.06.322"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2005.08.026"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10043"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.21119","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.21119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T01:04:22Z","timestamp":1700010262000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.21119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,29]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1002\/hed.21119"],"URL":"https:\/\/doi.org\/10.1002\/hed.21119","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,29]]}}}