{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:07:44Z","timestamp":1782950864330,"version":"3.54.5"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,8,18]],"date-time":"2009-08-18T00:00:00Z","timestamp":1250553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background.<\/jats:title>\n                    <jats:p>Our aim was to evaluate the therapeutic outcomes of patients with squamous cell carcinoma of the tonsil that underwent tonsillectomies followed by radiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>A search of the database maintained within the Department of Radiation Oncology at The University of Texas M. D. Anderson Cancer Center identified 120 patients with carcinoma of the tonsil who were irradiated between 1979 and 2004 following total gross removal of their disease by tonsillectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Thirty\u2010six patients had stage III disease and 64 patients had stage IV disease. Only 12 patients received systemic chemotherapy. With median follow\u2010up of 51 months, the 5\u2010year local\u2010regional control rate, recurrence\u2010free survival rate, and overall survival rates were 97%, 92%, and 86%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>Patients who undergo tonsillectomies resulting in total gross removal of their primary disease followed by radiation have excellent outcomes. Our common practice is to deliver 66 Gy to the tonsillar bed. This practice has resulted in extremely high local control rates. \u00a9 2009 Wiley Periodicals, Inc. Head Neck, 2010<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.21207","type":"journal-article","created":{"date-parts":[[2009,8,18]],"date-time":"2009-08-18T16:16:49Z","timestamp":1250612209000},"page":"473-480","source":"Crossref","is-referenced-by-count":13,"title":["Outcomes of patients with tonsillar carcinoma treated with post\u2010tonsillectomy radiation therapy"],"prefix":"10.1002","volume":"32","author":[{"given":"Gokcen","family":"Yildirim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William H.","family":"Morrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David I.","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erich M.","family":"Sturgis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassiliki A.","family":"Papadimitrakopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam S.","family":"Garden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,8,18]]},"reference":[{"key":"e_1_2_7_2_2","unstructured":"Cancer Registry Public Information Data: 1999\u20132002 WONDER On\u2010line Database.United States Department of Health and Human Services National Program of Cancer Registries Centers for Disease Control and Prevention.2005."},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22963"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20998"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.9.709"},{"key":"e_1_2_7_6_2","unstructured":"Clinical Indicators Compendium.American Academy of Otolaryngology\u2010Head and Neck Surgery1999. p.17."},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200011000-00006"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199811000-00004"},{"key":"e_1_2_7_9_2","volume-title":"manual for staging of cancer","author":"American Joint Committee on Cancer staging","year":"2002"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.12.3010"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(200005)22:3<294::AID-HED13>3.0.CO;2-9"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00291-5"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199807000-00012"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.11.2219"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01613-3"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10567"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00291-0"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199505000-00016"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2002.00618.x"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(89)90481-1"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00321-0"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.coc.0000209510.19360.f9"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.7.583"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-997084"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199501000-00013"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.12.1220"},{"key":"e_1_2_7_27_2","first-page":"299","volume-title":"Management of head and neck cancer","author":"Million RR","year":"1984"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032641"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032646"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.02.133"},{"key":"e_1_2_7_31_2","unstructured":"ForastiereAA AngK BrizelD et al.NCCN Clinical Practice Guidelines in Oncology: Head and Neck Cancers V. 2.2008."},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23486"}],"container-title":["Head &amp; 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