{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:09:54Z","timestamp":1772118594870,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Background.<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>The objective of this study was to identify the preoperative risk factors for patients in need of a sternotomy in the management of mediastinal goiters in order to provide better preoperative planning and patient consent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Methods.<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>We analyzed 98 patients who underwent surgery for mediastinal goiters (goiters extending below the thoracic inlet \u22653 cm with the neck in hyperextension) between 1995 and 2008. Twelve (12.2%) of the patients required a sternotomy. The patients' features were analyzed by the surgical approach performed. Logistic regression analysis was used to study which variables were influencing the surgical strategy. The receiver operating characteristic (ROC) curves were designed when appropriate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Results.<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>\n                      The analysis disclosed the following risk factors: radiologic extension of mediastinal goiters below the aortic arch (odds ratio [OR] = 32.87; 95% confidence interval [CI] = 4.04\u2013267.12;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .0001); posterior mediastinum involvement for mediastinal goiters with subaortic extension (OR = 7.2; 95% CI = 1.52\u201334.14;\n                      <jats:italic>p<\/jats:italic>\n                      = .0244); history of mediastinal goiters before surgery (for mediastinal goiters aged &gt;160 months: OR = 22.8; 95% CI = 5.28\u201398.53;\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:italic>Conclusions.<\/jats:italic>\n                    <\/jats:title>\n                    <jats:p>Sternotomy need for mediastinal goiter removal can be predicted; in such cases surgeons should not hesitate to perform it for minimizing complications. \u00a9 2009 Wiley Periodicals, Inc. Head Neck, 2010<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.21303","type":"journal-article","created":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T14:34:03Z","timestamp":1259678043000},"page":"1131-1135","source":"Crossref","is-referenced-by-count":34,"title":["Preoperative predictors of sternotomy need in mediastinal goiter management"],"prefix":"10.1002","volume":"32","author":[{"given":"Claudio","family":"Casella","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Pata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Cappelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Salerni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,23]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.135.4.467"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31264-0"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930600313"},{"key":"e_1_2_7_5_2","first-page":"196","article-title":"Substernal and intrathoracic goiter. Reconstruction of surgical approach","volume":"49","author":"Sand ME","year":"1983","journal-title":"Am Surg"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1992.01420050137018"},{"key":"e_1_2_7_7_2","first-page":"826","article-title":"Surgical management of substernal goiter: analysis of 237 patients","volume":"61","author":"Torre G","year":"1995","journal-title":"Am Surg"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2007.02.003"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00353749"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-1433.2003.02670.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-008-3768-9"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-006-0011-y"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-008-0338-y"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-007-3659-5"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-004-2823-4"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.01.039"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20102"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-924440"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-008-9466-3"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)62645-8"},{"key":"e_1_2_7_21_2","first-page":"969","article-title":"Rationale for the operative management of substernal goiters","volume":"94","author":"Allo MD","year":"1983","journal-title":"Surgery"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7216-0139-7.50037-5"},{"key":"e_1_2_7_23_2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1177\/000313480206800306","article-title":"The clinical presentation and operative management of nodular and diffuse substernal thyroid disease","volume":"68","author":"Hedayati N","year":"2002","journal-title":"Am Surg"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.21303","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.21303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T21:11:52Z","timestamp":1700601112000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.21303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,23]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1002\/hed.21303"],"URL":"https:\/\/doi.org\/10.1002\/hed.21303","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.9534968.10199055","asserted-by":"object"}]},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,23]]}}}