{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:55:57Z","timestamp":1761540957792},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,2,9]],"date-time":"2010-02-09T00:00:00Z","timestamp":1265673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background.<\/jats:title><jats:p>The purpose of this study was to compare the patterns of failure focusing on the distribution of local\u2010regional recurrence among patients treated postoperatively with conventional radiotherapy (RT) and intensity\u2010modulated radiotherapy (IMRT) for head and neck cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>The records of 130 patients treated by surgery and postoperative radiation therapy for squamous cell carcinoma of the head and neck were reviewed. Seventy\u2010eight patients (60%) were treated using conventional RT and 52 patients (40%) were treated using IMRT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>The 3\u2010year estimates of local\u2010regional control were 70% and 73% among patients treated by conventional RT and IMRT, respectively (<jats:italic>p<\/jats:italic> = .33). Among the local\u2010regional recurrences in the IMRT group, 9 were in\u2010field recurrences occurring within the physician\u2010designated clinical target volume (CTV), and 4 were marginal recurrences involving the contralateral neck adjacent to the spared parotid gland (3 patients) and the retropharyngeal\/retrostyloid lymph node region (1 patient).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Our study showed that conventional RT and IMRT result in similar rates of local\u2010regional control. The implications for CTV design are discussed herein. \u00a9 2010 Wiley Periodicals, Inc. Head Neck, 2010<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.21343","type":"journal-article","created":{"date-parts":[[2010,2,9]],"date-time":"2010-02-09T16:39:05Z","timestamp":1265733545000},"page":"1452-1459","source":"Crossref","is-referenced-by-count":16,"title":["Misses and near\u2010misses after postoperative radiation therapy for head and neck cancer: Comparison of IMRT and non\u2010IMRT techniques in the CT\u2010simulation era"],"prefix":"10.1002","volume":"32","author":[{"given":"Allen M.","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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