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In the test group, the submandibular salivary gland was transferred to submental space before radiotherapy (XRT) and shielded. Salivary gland functions were evaluated by the amount of saliva and a quality of life questionnaire before and after XRT and 3 and 60 months after XRT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 5 years, the trapping and excretion functions of salivary gland were significantly better in the test group (<jats:italic>p<\/jats:italic> = .000 and <jats:italic>p<\/jats:italic> = .000). The mean weight of saliva after XRT was heavier (1.65 g vs 0.73 g, <jats:italic>p<\/jats:italic> = .000), and the incidence of xerostomia was lower in the test group, with no difference in 5\u2010year survival and neck nodal recurrence between the 2 groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Salivary gland transfer procedure prevents XRT\u2010induced xerostomia and improves quality of life of patients with NPC. \u00a9 2010 Wiley Periodicals, Inc. Head Neck, 2010<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.21461","type":"journal-article","created":{"date-parts":[[2010,7,13]],"date-time":"2010-07-13T19:30:42Z","timestamp":1279049442000},"page":"389-395","source":"Crossref","is-referenced-by-count":29,"title":["Submandibular salivary gland transfer for the prevention of radiation\u2010induced xerostomia in patients with nasopharyngeal carcinoma: 5\u2010Year 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