{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:45:40Z","timestamp":1786977940775,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,8,17]],"date-time":"2011-08-17T00:00:00Z","timestamp":1313539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with small, low\u2010\/intermediate\u2010risk parotid cancers, treated with surgery, and who have the single prognostic factor of close and\/or positive margins, constitute an unusual subset. This study evaluates local control and morbidity associated with postoperative radiation therapy for low\/intermediate grade parotid cancer in these patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between 1999 and 2006, 17 patients underwent postoperative radiation therapy at Beth Israel Medical Center for acinic cell carcinoma or low\u2010intermediate\u2010grade mucoepidermoid carcinoma of the parotid with close\/positive margins. Pathology, treatment, and follow\u2010up data were retrospectively analyzed for morbidity and local control. Two\u2010 and 5\u2010year estimates of survival outcomes were performed followed by an analysis of complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no local failures and no significant long\u2010term complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with small, low\u2010risk cancer of the parotid gland have excellent local control and low treatment\u2010related morbidity when receiving postoperative radiation therapy for positive or close margins of resection. \u00a9 2011 Wiley Periodicals, Inc. Head Neck, 2012<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hed.21843","type":"journal-article","created":{"date-parts":[[2011,8,17]],"date-time":"2011-08-17T14:48:02Z","timestamp":1313592482000},"page":"953-955","source":"Crossref","is-referenced-by-count":30,"title":["Postoperative radiation therapy for small, low\u2010\/intermediate\u2010grade parotid tumors with close and\/or positive surgical margins"],"prefix":"10.1002","volume":"34","author":[{"given":"Samuel M.","family":"Richter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Friedmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed F.","family":"Mourad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth S.","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Persky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis B.","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,17]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1989.01860270058015"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1991.01870150075010"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(96)00464-6"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2004.01.017"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24259"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870030054008"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197910)44:4<1434::AID-CNCR2820440439>3.0.CO;2-H"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001060170031"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910101)67:1<172::AID-CNCR2820670129>3.0.CO;2-X"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24259"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.03.018"},{"key":"e_1_2_6_13_2","first-page":"342","article-title":"Radiation therapy for patients of malignant salivary gland tumors with positive surgical margins","volume":"170","author":"Sakata K","year":"1994","journal-title":"Strahlenther Onkol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1002\/(SICI)1097-0142(19990501)85:9<2057::AID-CNCR24>3.0.CO;2-F","article-title":"The development of a prognostic score for patients with parotid carcinoma","volume":"89","author":"Vander Poorten VLM","year":"1999","journal-title":"Cancer"},{"key":"e_1_2_6_15_2","first-page":"589","volume-title":"Head and neck cancer: a multidisciplinary approach","author":"Futran ND","year":"2009"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.112484"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000135326.50939.C1"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.21843","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.21843","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T10:09:13Z","timestamp":1700561353000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.21843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,17]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1002\/hed.21843"],"URL":"https:\/\/doi.org\/10.1002\/hed.21843","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,17]]}}}