{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:55:33Z","timestamp":1764996933075},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,11,23]],"date-time":"2011-11-23T00:00:00Z","timestamp":1322006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Squamous cell carcinoma of the soft palate (SCCSP) is uncommon. The aim of this study was to report our experience and identify factors predictive of outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 1976 and 2005, 186 patients with SCCSP were treated with curative intent. In all, 150 patients had primary surgery, of whom 112 patients (75%) had cT1\/T2 tumors and 103 patients (69%) had cN0 necks. Overall survival (OS), disease\u2010specific survival (DSS), and recurrence\u2010free survival (RFS) were determined by the Kaplan\u2013Meier method and factors predictive of outcome were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five\u2010year OS, DSS, and RFS for surgical patients were, respectively, 52%, 71%, and 56%. DSS for cT1T2N0 and cT1T2N+ were 79% and 56%, respectively. For OS and DSS, multivariate analysis showed cN classification was predictive of outcome. For RFS and distant RFS, margin status was a significant predictor, whereas the cT classification was a significant predictor for local RFS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Outcomes of patients with early\u2010stage SCCSP managed by surgery were excellent. These patients may be suitable for transoral robotic or endoscopic surgical procedures. \u00a9 2011 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic>, 2011<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.21878","type":"journal-article","created":{"date-parts":[[2011,11,23]],"date-time":"2011-11-23T07:30:11Z","timestamp":1322033411000},"page":"1071-1080","source":"Crossref","is-referenced-by-count":14,"title":["Surgical management of squamous cell carcinoma of the soft palate: Factors predictive of outcome"],"prefix":"10.1002","volume":"34","author":[{"given":"N. 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