{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:12:24Z","timestamp":1787976744478,"version":"build-2784847793"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,11,11]],"date-time":"2011-11-11T00:00:00Z","timestamp":1320969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head & Neck"],"published-print":{"date-parts":[[2012,8]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>To investigate the relationship between paraglottic space (PGS) invasion and lymph node metastasis in patients undergoing supracricoid partial laryngectomy.<\/jats:p><\/jats:sec>Methods<\/jats:title>The study included 98 subjects with squamous cell carcinoma of the glottis.<\/jats:p><\/jats:sec>Results<\/jats:title>The PGS invasion rate was 60.2% (59\/98), and a significant correlation was found between PGS invasion and cervical lymph node metastasis (p<\/jats:italic> = .022). Fifteen of the 59 patients (25.4%) with PGS invasion, only 3 of the 39 patients (7.7%) without any evidence of PGS invasion had lymph node metastasis. Furthermore, a significant correlation was also found between PGS invasion and T classification (p<\/jats:italic> < .001), vocal cord mobility (p<\/jats:italic> < .001), and subglottic extension (p<\/jats:italic> = .014), and patients with no evidence of PGS invasion possibly had a survival benefit (5\u2010year disease\u2010specific survival rate, 84% vs 64%; p<\/jats:italic> = .118).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This study shows that PGS invasion is significantly related to cervical lymph node metastasis in patients undergoing supracricoid partial laryngectomy. \u00a9 2011 Wiley Periodicals, Inc. 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