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These life\u2010sustaining functions may be produced by a central neural sensorimotor system that shares certain neuroanatomic networks while maintaining separate neural functional systems and network structures. Current understanding of development, maturation, underlying neural correlates, and integrative factors are discussed in light of currently available imaging modalities and recently emerging interventions. Exercise and an array of additional treatments together seem to provide promising translational pathways for evidence\u2010based innovation, novel habilitation, and rehabilitation strategies and delay, or even prevent neuromuscular decline cross\u2010cutting functions and supporting quality of life throughout increasingly enduring lifespans. \u00a9 2011 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic>, 2011<\/jats:p>","DOI":"10.1002\/hed.21902","type":"journal-article","created":{"date-parts":[[2011,9,9]],"date-time":"2011-09-09T20:44:28Z","timestamp":1315601068000},"source":"Crossref","is-referenced-by-count":6,"title":["Upper aerodigestive tract neurofunctional mechanisms: Lifelong evolution and exercise"],"prefix":"10.1002","volume":"33","author":[{"given":"JoAnne","family":"Robbins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,9]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0095-4470(19)31123-4","article-title":"Coarticulation in recent speech production models","volume":"5","author":"Kent RD","year":"1977","journal-title":"J Phonetics"},{"key":"e_1_2_7_3_2","first-page":"425","article-title":"Coordination of deglutitive vocal cord closure and oral\u2010pharyngeal swallowing events in the elderly","volume":"8","author":"Zamir Z","year":"1996","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"e_1_2_7_4_2","first-page":"3","article-title":"Morphological criteria of growth and maturation of the nervous system in man","volume":"39","author":"Yakovlev PI","year":"1962","journal-title":"Res Publ Assoc Res Nerv Ment Dis"},{"key":"e_1_2_7_5_2","first-page":"98","article-title":"Studies on physiological properties of synaptic systems of the cerebral cortex","volume":"117","author":"Anokhin PK","year":"1964","journal-title":"[Article in Russian] Tr Inst Norm Patol Fiziol"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21845"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2009.09.005"},{"key":"e_1_2_7_8_2","volume-title":"A neurobiologic view of speech production and the dysarthrias","author":"Netsell R","year":"1986"},{"key":"e_1_2_7_9_2","first-page":"350","article-title":"Prospective study of pneumonia hospitalizations and mortality of U.S. older people: the role of chronic conditions, health behaviors, and nutritional status","volume":"104","author":"LaCroix AZ","year":"1989","journal-title":"Public Health Rep"},{"key":"e_1_2_7_10_2","unstructured":"US Census Bureau. 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