{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T21:58:15Z","timestamp":1776808695684,"version":"3.51.2"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,4,7]],"date-time":"2012-04-07T00:00:00Z","timestamp":1333756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Head &amp; Neck"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to analyze the treatment of recurrent parotid gland cancers with radioactive iodine (<jats:sup>125<\/jats:sup>I) seed implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen patients with recurrent previously irradiated parotid gland cancers were treated with postoperative <jats:sup>125<\/jats:sup>I seed implantation between April 2004 and June 2009. Local control, survival rates, and side effects were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 3\u2010year and 5\u2010year local control rates were 67% and 53.6%, and the overall survival rates were 76.2% and 66.7%, respectively. Four patients with House\u2013Brackman (H\u2013B) grade IV cancer recovered to grade II during follow\u2010up. Four patients (26.7%) developed grade IV skin ulceration. Two patients (13.3%) developed moderate fibrosis of the subcutaneous tissues, and 2 patients (13.3%) had hearing loss for 1 year after brachytherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study showed excellent local control and a good survival rate in patients who received <jats:sup>125<\/jats:sup>I brachytherapy. These findings should be interpreted cautiously due to the small number of patients and the relatively short follow\u2010up. \u00a9 2012 Wiley Periodicals, Inc. <jats:italic>Head Neck<\/jats:italic>, 2012<\/jats:p><\/jats:sec>","DOI":"10.1002\/hed.21955","type":"journal-article","created":{"date-parts":[[2012,4,8]],"date-time":"2012-04-08T06:46:26Z","timestamp":1333867586000},"page":"1445-1449","source":"Crossref","is-referenced-by-count":13,"title":["Preliminary results of <sup>125<\/sup>I interstitial brachytherapy for locally recurrent parotid gland cancer in previously irradiated patients"],"prefix":"10.1002","volume":"34","author":[{"given":"Lei","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tieli","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingwei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangyan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,7]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810701112"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2003.10.002"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(99)70323-2"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(86)90314-7"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198509000-00007"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(90)90304-3"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890080309"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198610000-00014"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.12.055"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.12.1317"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2006.11.007"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2002.0332"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2008.04.013"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00069-3"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-4096.2001.01610.x"},{"key":"e_1_2_5_17_2","volume-title":"National Institutes of Health National Cancer Institute","author":"Services U.S. Department of Health","year":"2003"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22647"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.07.125"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.10.044"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.11.3556"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01745-X"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8140(95)01620-V"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01456-0"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.70"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01637-6"}],"container-title":["Head &amp; Neck"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhed.21955","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hed.21955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T15:52:25Z","timestamp":1700581945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hed.21955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,7]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1002\/hed.21955"],"URL":"https:\/\/doi.org\/10.1002\/hed.21955","archive":["Portico"],"relation":{},"ISSN":["1043-3074","1097-0347"],"issn-type":[{"value":"1043-3074","type":"print"},{"value":"1097-0347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,7]]}}}